Role of ligand backbone of tridentate Schiff-base on complex nuclearity and bio-relevant catalytic activities of zinc(II) complexes: Experimental and theoretical investigations

Phosphatase models: Synthesis, structure and catalytic activity of zinc complexes derived from a phenolic Mannich-base ligand

“…S20 and S21, respectively. The dinuclear complexes were found to dissociate into two mononuclear moieties; and we report only the mass spectrum of 1 ([C 13 Fig. S23.…”

“…Over the years, synthetic Zn(II) (and also other transition metal) complexes have been judiciously studied as phosphate ester models taking into account their extraordinary Lewis acidity, redox rigidity, nucleophile generation, leaving group stabilization and physiological relevancy [11,12]. However, among the numerous catalytically promiscuous Zn(II) derivatives [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] some complexes show low activity, others require rigorous synthetic conditions or have high toxicity. Therefore the development of new efficient metallocatalysts is still a tough challenge in the field of biocatalysis.…”

Synthesis and characterization of Schiff bases NBBA, MNBA and CNBA

“…Schiff base ligands are important class of organic molecules that could be referred to as seen as ‘privileged ligands due to their simple and easy preparation route from the reaction of aldehydes or ketones with amines’. They have high tendency of forming coordination compounds with metals of varying oxidation states [ 1 , 2 , 3 , 4 , 5 , 6 ]. Most Schiff base compounds have been prepared by reaction of a carbonyl compound, especially an aldehyde, and a primary amine with the elimination of a water molecule [7] .…”

Ligand‐Flexibility Controlled and Solvent‐Induced Nuclearity Conversion in CuII‐Based Catecholase Models: A Deep Insight Through Combined Experimental and Theoretical Investigations

“…Coordination complexes with different nuclearities are interesting for their potential application in different fields such as catalysis, modelling of metallobiosites, supramolecular chemistry, magnetochemistry etc Ligand flexibility, solvent, pH and anions are observed to be crucial factors in generating complexes with different nuclearity and structural diversity. Recently, by using flexible tridentate Schiff‐base ligands, we were able to synthesize complexes featuring different nuclearity, which exhibited quite different photophysical and/or biorelevant catalytic activities . Reduced Schiff bases have been attracting special interest from coordination chemists recently because of their greater flexibility over their Schiff base counterparts owing to the reduction of the more rigid azomethine (–CH=N–) fragment to the less constrained –CH 2 –NH– moiety .…”