Role of optical coherence tomography angiography in diagnostics of early choroidal melanoma and circumscribed choroidal hemangioma

Нероев, В. В.; Saakyan, S.V.; Myakoshina, E. B.; Okhotsimskaya, T. D.; Fadeeva, V. A.

doi:10.17116/oftalma201813434

Cited by 17 publications

(18 citation statements)

References 15 publications

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“…The synthetic QS-inhibiting substances include the preparations of 5-fluorouracil, azithromycin, poly(ethylene glycol), furanone derivatives, thiazolidinone derivatives, etc. 8 Bacteria constantly modulate gene expression in response to changing environmental conditions. Many ways of regulating gene transcription respond to internal signaling molecules, metabolites, and environmental signals.…”

Section: Introductionmentioning

confidence: 99%

“…The disclosure of the functions of the multiple ECF σ-factors present in many genomes poses a huge challenge for future research. 7 , 8 …”

Section: Introductionmentioning

confidence: 99%

“…The increased cellular density of a microbial community or biofilm and the consequent accumulation of signaling or QS molecules help the metabolic activity of microbial cells, including their tolerance to antimicrobials and synthesis of virulence factors, adapt better by synchronizing their expression of different genes at a particular cell density, according to each step of the infectious process. 8 The prognosis of these chronic infections, compared with a metastatic phenomenon, following biofilm development on cellular substrata and biomaterials used in medicine, is worsened by a particular property—behavioral resistance or tolerance, even though the component cells tested in suspension (by the standard method) may be susceptible to some antibiotics. In this context, the research to find and test new preventive or therapeutic anti-infectious strategies has become a top scientific priority.…”

Section: Introductionmentioning

confidence: 99%

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Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis

Feng

et al. 2020

ACS Omega

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This study is a bioinformatics assay on the microbial genome of Bacteroides thetaiotaomicron . The study focuses on the problem of quorum sensing as a result of adverse factors such as chemotherapy and antibiotic therapy. In patients with severe intestinal diseases, two strains of microorganisms were identified that were distinguished as new. Strains were investigated by conducting genome sequencing. The current concepts concerned with the quorum sensing system regulation by stationary-phase sigma factor and their coregulation of target genes in B. thetaiotaomicron were considered. The study suggested using bioinformatics data for the diagnosis of gastrointestinal disorders. In the course of the study, 402 genes having a greater than twofold change were identified with the 95% confidence level. The shortest and longest coding genes were predicted; the noncoding genes were detected. Biological pathways (KEGG pathways) were classified into the following categories: cellular processes, environmental information processing, genetic information processing, human disease, metabolism, and organismic systems. Among notable changes in the biofilm population observed in parallel to the planktonic B. thetaiotaomicron was the expression of genes in the polysaccharide utilization loci that were involved in the synthesis of O-glycans.

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Section: Introductionmentioning

confidence: 99%

“…The disclosure of the functions of the multiple ECF σ-factors present in many genomes poses a huge challenge for future research. 7 , 8 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis

Feng

et al. 2020

ACS Omega

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“…The diagnosis was confirmed by PCR analysis of serum. Many children suffered from mononucleosis-like illness 18 .…”

Section: Figure1mentioning

confidence: 99%

Features of folate cycle disorders in children with ASD

Maltsev

2020

Bangladesh J Med Sci

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Aim: to show the effect of genetically determined folate cycle deficiency in children with autism spectrum disorders (ASD). Participants: 89 children (57 boys; 32 girls, Ukraine, 2-10 years old); participants were diagnosed with ASD. The control group consisted of 34 children with ASD. Diagnostic methods:polymerase chain reaction (PCR), complex immunological research, diagnosis of infection, determination of biomarkers. Results and discussion:Hyperhomocysteinemia was revealed in 87% of cases (p <0.05; Z <Z0.05).The indicated form of immunodeficiency was noted among 91% participants in the study, while only in 27% children of the control group had a similar immunological phenotype.The serum concentration of folic acid was increased in 64%, and reduced in 21% of cases. An increase of vitamin B12 also occurred in 64%, and vitamin B6 - only in 43% of cases. Bangladesh Journal of Medical Science Vol.19(4) 2020 p.737-742

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“…Uveal melanoma is the most frequently occurring intraocular tumor threatening not only to eyesight but alsoto the life of the patient. Despite the fact that uveal melanoma is quite rare and its share in the overall oncopathology is insignificant (3,7%), it represents75% -94%of all malignant eye neoplasms, while the part of this tumor in the death rate from metastasis in all types of cancer is 15% [4][5][6].…”

Section: The Incidence and Prevalence Of Uveal Melanoma In The Republmentioning

confidence: 99%

The Incidence and Prevalence of Uveal Melanoma in the Republic of Kazakhstan

Balmukhanova¹,

Seitkazina²,

Chingissova³

2019

OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF KAZAKHST

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Abzhanov Arkhat, prof. (Boston, USA), Abelev S.K., prof. (Moscow, Russia), Aitkhozhina N.А., prof., academician (Kazakhstan) Akshulakov S.K., prof., academician (Kazakhstan) Alchinbayev М.K., prof., academician (Kazakhstan) Batpenov N.D., prof., corr. member (Kazakhstan) Berezin V.Ye., prof., corr. member. (Kazakhstan) Bersimbayev R.I., prof., academician (Kazakhstan) Berkinbaev S.F., prof. (Kazakhstan) Bisenbayev А.K., prof., academician (Kazakhstan) Bishimbayeva N.K., prof., academician (Kazakhstan) Botabekova Т.K., prof., corr. member. (Kazakhstan) Bosch Ernesto, prof. (Spain) Davletov Kairat, PhD, associate professor, executive Secretary Dzhansugurova L.B., Cand. biol., prof. (Kazakhstan) Ellenbogen Adrian, prof. (Tel-Aviv, Israel), Zhambakin K.Zh., prof., academician (Kazakhstan), deputy editor-in-chief Ishchenko Alexander, prof. (Villejuif, France) Isayeva R.B., prof. (Kazakhstan) Kaydarova D.R., prof., academician (Kazakhstan) Kokhmetova A., prof., corr. member (Kazakhstan) Kuzdenbayeva R.S., prof., academician (Kazakhstan) Lokshin V.N., prof., corr. member (Kazakhstan) Los D.А., prof. (Moscow, Russia) Lunenfeld Bruno, prof. (Israel) Makashev E.K., prof., corr. member (Kazakhstan) Mitalipov Sh.M. (America) Muminov Т.А., prof., academician (Kazakhstan) Ogar N.P., prof., corr. member (Kazakhstan) Omarov R.T., cand. biol., prof. (Kazakhstan) Prodeus A.P., prof. (Russia) Purton Saul, prof. (London, UK) Rakhypbekov Т.K., prof., corr. member. (Kazakhstan) Saparbayev Мurat, prof. (Paris, France) Sarbassov Dos, prof. (Houston, USA) Turysbekov E.K., cand. biol., assoc. prof. (Kazakhstan) Sharmanov A.T., prof. (USA) News of the National Academy of Sciences of the Republic of Kazakhstan. Series of biology and medicine.

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Role of optical coherence tomography angiography in diagnostics of early choroidal melanoma and circumscribed choroidal hemangioma

Cited by 17 publications

References 15 publications

Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis

Quorum Sensing System in Bacteroides thetaiotaomicron Strain Identified by Genome Sequence Analysis

Features of folate cycle disorders in children with ASD

The Incidence and Prevalence of Uveal Melanoma in the Republic of Kazakhstan

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