Role of the periaqueductal grey in vocal expression of emotion

Jürgens, Uwe; Pratt, R K

doi:10.1016/0006-8993(79)90830-8

Cited by 321 publications

(112 citation statements)

References 28 publications

Supporting

Mentioning

106

Contrasting

Unclassified

Order By: Relevance

“…The periaqueductal gray is an obligatory relay station for the control of vocalization. By injection of an anterograde neurotracer it could be demonstrated that efferents arising here reach the complete lateral reticular formation of the medulla oblongata, including the nucleus ambiguus and the region in which this nucleus is embedded (Jfirgens and Pratt 1979). As illustrated in our experiments in bats, this region of the lateral reticular formation is, in addition,reciprocally interconnected with the nucleus ambiguus.…”

Section: Vocalization Pathwayssupporting

confidence: 61%

“…This nucleus is not directly incorporated in the somatomotor or visceromotor fiber tracts of the extrapyramidal or pyramidal motor systems. But it is connected with all prosencephalic vocalization centers, and lesions in this nucleus mute the animals (Jfirgens and Pratt 1979). The periaqueductal gray is an obligatory relay station for the control of vocalization.…”

Section: Vocalization Pathwaysmentioning

confidence: 99%

“…Reciprocal interconnection has been demonstrated between the nucleus ambiguus and the parabrachial nuclei (Saper and Loewy 1980;Kalia 1981). The above mentioned periaqueductal gray is known to be part of the 'descending vocalization pathway' (Jfirgens and Pratt 1979), whereas the parabrachial nuclei and parts of the nucleus of the solitary tract are involved in the generation of respiratory rhythm (von Euler 1983).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat,Rhinolophus rouxi

Rübsamen¹,

Schweizer²

1986

J. Comp. Physiol.

View full text Add to dashboard Cite

Summary. 1. Horseradish peroxidase was applied by iontophoretic injections to physiologically identified regions of the laryngeal motor nucleus, the nucleus ambiguus in the CF/FM bat Rhinolophus rouxi.2. The connections of the nucleus ambiguus were analysed with regards to their possible functional significance in the vocal control system, in the respiration control system, and in mediating information from the central auditory system.3. The nucleus ambiguus is reciprocally interconnected with nuclei involved in the generation of the vocal motor pattern, i.e., the homonomous contralateral nucleus and the area of the lateral reticular formation. Similarly, reciprocal connections are found with the nuclei controlling the rhythm of respiration, i.e., medial parts of the medulla oblongata and the parabrachial nuclei.4. Afferents to the nucleus ambiguus derive from nuclei of the 'descending vocalization system' (periaqueductal gray and cuneiform nuclei) and from motor control centers (red nucleus and frontal cortex).5. Afferents to the nucleus ambiguus, possibly mediating auditory influence to the motor control of vocalization, come from the superior colliculus and from the pontine nuclei. The efferents from the pontine nuclei are restricted to rostral parts of the nucleus ambiguus, which hosts the motoneurons of the cricothyroid muscle controlling the call frequency.

show abstract

Section: Vocalization Pathwayssupporting

confidence: 61%

Section: Vocalization Pathwaysmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat,Rhinolophus rouxi

Rübsamen¹,

Schweizer²

1986

J. Comp. Physiol.

View full text Add to dashboard Cite

show abstract

“…ambiguus have been revealed mainly by electrical stimulation (e.g. Novick and Griffin 1961;Suthers and Fattu 1982;Suga et al 1973;Jiirgens 1976;Jiirgens and Pratt 1979) or chemical stimulation (Richter and Jtirgens 1986;Jiirgens and Richter 1986) to determine brain areas where species-specific vocalizations can be elicited. It is only in primates that the brain structures involved in sound production have been investigated at all levels of the central nervous system (Jfirgens 1988).…”

Section: Introductionmentioning

confidence: 99%

“…An important role is attributed to the central gray of the midbrain and structures of the adjacent reticular formation as centers where all information from higher levels (e.g. hypothalamus, gyrus cinguli) is integrated and transmitted to the nucleus ambiguus (Jiirgens and Pratt 1979). Kirzinger and Jfirgens (1985) demonstrated that ablation of brain structures above the level of the periaqueductal gray (PAG) did not alter the spectral composition of spontaneously emitted calls, suggesting that motor coordination of laryngeal muscles is controlled below the mesencephalic level.…”

Section: Introductionmentioning

confidence: 99%

Neural control of vocalization in bats: mapping of brainstem areas with electrical microstimulation eliciting species-specific echolocation calls in the rufous horseshoe bat

Schuller

Radtke‐Schuller

1990

Exp Brain Res

View full text Add to dashboard Cite

Summary. 1. The functional role of brainstem structures in the emission of echolocation calls was investigated in the rufous horseshoe bat, Rhinolophus rouxi, with electrical low-current microstimulation procedures. 2. Vocalizations without temporal and/or spectral distortions could be consistently elicited at low threshold currents (typically below 10 gA) within three clearly circumscribed brainstem areas, namely, the deep layers and ventral parts of the intermediate layers of the superior colliculus (SC), the deep mesencephalic nucleus (NMP) in the dorsal and lateral midbrain reticular formation and in a distinct area medial to the rostral parts of the dorsal nucleus of the lateral lemniscus. The mean latencics in the three vocal areas between the start of the electrical stimulus and the elicited vocalizations were 47 msec, 38 msec and 31 msec, respectively. 3. In pontine regions and the cuneiform nucleus adjacent to these three vocal areas, thresholds for eliciting vocalizations were also low, but the vocalizations showed temporal and/or spectral distortions and were often accompanied or followed by arousal of the animal. 4. Stimulus intensity systematically influenced vocalization parameters at only a few brain sites. In the caudo-ventral portions of the deep superior colliculus the sound pressure level of the vocalizations systematically increased with stimulus intensity. Bursts of multiple vocalizations were induced at locations ventral to the rostral parts of the cuneiform nucleus. No stimulus-intensity dependent frequency changes of the emitted vocalizations were observed. 5. The respiratory cycle was synchronized to the electrical stimuli in all regions where vocalizations could be elicited as well as in more ventrally and medially adjacent areas not yielding vocalizations on stimulation. 6. The possible functional involvement of the "vocal" structures in the audio-vocal feedback system of the Dopplercompensating horseshoe bat is discussed.

show abstract

Pontine and medullary projections to the nucleus retroambiguus: A wheat germ agglutinin-horseradish peroxidase and autoradiographic tracing study in the cat

Gerrits¹,

Holstege²

1996

J. Comp. Neurol.

View full text Add to dashboard Cite

The nucleus retroambiguus (NRA) in the caudal medulla oblongata plays a role in expiration, vocalization, vomiting, and possibly lordosis. The present study tried to determine which structures, in turn, control the NRA. One cell group is the periaqueductal gray (PAG), which is considered to be the final integrator of defensive and aggressive behaviors, micturition, vocalization, and lordosis. Structures rostral to the PAG seem to bypass the NRA. With respect to the existence of cell groups caudal to the PAG projecting to the NRA, the situation is less clear. Therefore, in five adult female cats, injections of wheat germ agglutinin-horseradish peroxidase were centered on the NRA, and the resulting retrogradely labeled neurons were plotted. In the areas containing retrogradely labeled cells, the anterograde autoradiographic tracer [3H]-leucine was injected in 66 cats. The combined results demonstrated that NRA afferents not only originate from the PAG but also from specific cell groups in the pontine and medullary lateral tegmental field, i.e., the ventrolateral parabrachial nucleus, the nucleus Kölliker-Fuse, the retrotrapezoid nucleus, and the ventrolateral part of the medulla caudal to the facial nucleus including the Bötzinger and pre-Bötzinger complex and the periambigual region. Afferents also originate from the solitary nucleus and two cell groups in the ventral part of the medullary medial tegmental field, one at the level of facial nucleus and one just rostral to the hypoglossal nucleus. It can be concluded that many respiratory-related cell groups have direct access to the NRA. The cell groups in the medial tegmental field, which have not yet been found to play an important role in respiration, might serve as relay for certain limbic system cell groups to reach the NRA in the context of specific emotional behavior.

show abstract

Role of the periaqueductal grey in vocal expression of emotion

Cited by 321 publications

References 28 publications

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat,Rhinolophus rouxi

Control of echolocation pulses by neurons of the nucleus ambiguus in the rufous horseshoe bat,Rhinolophus rouxi

Neural control of vocalization in bats: mapping of brainstem areas with electrical microstimulation eliciting species-specific echolocation calls in the rufous horseshoe bat

Pontine and medullary projections to the nucleus retroambiguus: A wheat germ agglutinin-horseradish peroxidase and autoradiographic tracing study in the cat

Contact Info

Product

Resources

About