Root surface reactions to TiF4and SnF2solutions in vitro: An ultrastructural study

Skartveit, Liv; Selvig, Knut A.; Tveit, Anne Bjørg

doi:10.3109/00016359109005905

Cited by 14 publications

(16 citation statements)

References 26 publications

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“…Schlueter et al [2007] demonstrated that TiF 4 was as effective as sodium fluoride in reducing the progression of erosive lesions in dentine. Application of TiF 4 to dentine specimens resulted in the formation of an electron-dense, acid-stable Ti-containing coating [Skartveit et al, 1991] as well as in increased retention of fluoride and titanium [Tveit et al, 1988;Skartveit et al, 1989a, b]. Furthermore, TiF 4 treatment was shown to be effective in decreasing dentine permeability since it probably modifies the smear layer of dentine discs to a dense and acid-resistant coating [Kazemi et al, 1999].…”

mentioning

confidence: 99%

Protective Effect of Different Tetrafluorides on Erosion of Pellicle-Free and Pellicle-Covered Enamel and Dentine

Wiegand¹,

Meier²,

Sutter³

et al. 2008

Caries Res

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The aim was to analyze the protective effects of titanium, zirconium and hafnium tetrafluorides on erosion of pellicle-free and pellicle-covered enamel and dentine in vitro. Eight groups of 20 specimens each of bovine enamel and bovine dentine were prepared. Half the specimens in each group were immersed in human saliva for 2 h for pellicle formation. Specimens were then left untreated (controls) or were treated for 120 s with TiF₄, ZrF₄ or HfF₄ solutions (0.4 or 1%) or 1.25% AmF/NaF gel. All specimens were eroded by exposure to hydrochloric acid, pH 2.6, for 25 min. Cumulative calcium release into the acid was monitored in consecutive 30-second intervals for 5 min, then at 2-min intervals up to a total erosion time of 25 min using the Arsenazo III procedure. Data were analyzed by ANOVA. 1% TiF₄ solution offered the best protective effect, especially in dentine (reduction of calcium loss about 50% at 25 min). 1% ZrF₄, 1% HfF₄ and 0.4% TiF₄ also reduced calcium loss, but to a lesser extent. Long-term effects were limited to dentine, while reduction of enamel erosion (about 25%) was restricted to 1-min erosion. The fluoride gel had a protective effect only in dentine. The efficacy of the tetrafluorides was influenced by the presence of the pellicle layer, in that the protection against dentine erosion by TiF₄ and ZrF₄ was greater on pellicle-covered specimens. Tetrafluoride solutions, especially 1% TiF₄, could decrease dental erosion, but were more effective on dentine than on enamel.

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mentioning

confidence: 99%

Protective Effect of Different Tetrafluorides on Erosion of Pellicle-Free and Pellicle-Covered Enamel and Dentine

Wiegand¹,

Meier²,

Sutter³

et al. 2008

Caries Res

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“…Through their acidity these solutions may also cause erosion. The extent of demineralization of the tooth surfaces depends on the concentration of the products and the duration of the application period, and can range from 10 to 20 m [Skartveit et al, 1991;Büyükylmaz et al, 1997b]. The additional enamel loss at application may have masked the potential of 1 and 4% TiF 4 solutions and gels used for erosion protection in some studies [Vieira et al, 2005;Vieira et al, 2006;Magalhães et al, 2008].…”

mentioning

confidence: 99%

In vitro Reduction of Dental Erosion by Low-Concentration TiF4 Solutions

et al. 2011

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The aims of this study were to compare daily versus single applications of low-concentration TiF₄ solutions for reduction of enamel erosion and to evaluate the enamel surface loss due to application of these solutions. Sixty bovine enamel samples were randomly divided into 2 groups: single versus daily treatment with TiF₄ solution (ST vs. DT), which were subdivided into 5 subgroups (n = 6): 0% (control); 0.1, 0.5, 0.75 and 1% TiF₄ concentration. Fluoride treatment was performed by immersing specimens in 10 ml of the TiF₄ solutions for 5 min and rinsing them with tap water for 30 s. ST specimens were treated once only, DT specimens were treated before each erosion cycle. All specimens were subjected to 4 erosion cycles: 6 immersions of 2 min in Sprite, tap water rinse for 1 min and storage in artificial saliva for 1.5 h. Erosive enamel loss was measured using light profilometry, after each fluoride treatment and each erosive cycle. The values of surface loss/gain at application of the TiF₄ solutions did not significantly differ from zero. At the end of the 4 erosion cycles, 0.5% showed the least (ST: 3.45 ± 0.27 µm, DT: 1.08 ± 1.69 µm) and 1% showed the most surface loss (ST: 4.87 ± 1.13 µm, DT: 6.56 ± 1.49 µm). A significant reduction of surface loss was found only for 0.5% DT (p = 0.009). Within the limitations of an in vitro study, it was concluded that multiple applications of a 0.5% TiF₄ solution significantly reduced enamel erosion in vitro and caused no enamel loss at application.

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“…The titanium ion has the ability to form complexes concomitantly with F ions and dental tissues 27 . As a result, TiF 4 action has been widely studied 19,[28][29][30] in Dentistry.…”

Section: Titanium Tetrafluoridementioning

confidence: 99%

“…However, TiF 4 , when administered enterally, does not show signs of systemic toxicity 33 . Although, even considering the acidity of the solution, the surface demineralization caused is partial 27 and may favor the penetration of fluoride into the mineralized tissue 34,35 .…”

Section: Titanium Tetrafluoridementioning

confidence: 99%

Titanium Tetrafluoride (TiF4) in the Treatment of Dental Erosion

Mantilla

Freitas

2018

J. Health Scie.

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Dental erosion is a multifactorial pathology that leads to dental substrate loss caused by its exposure to acids of non-bacterial origin. The process begins with a superficial demineralization of enamel, which, when continuously exposed to erosive solutions, can even lead to dentin exposure, causing aesthetic/functional problems to patients, besides increasing the chances of dentin hypersensitivity. Fluoride ResumoA erosão dental é uma patologia multifatorial que leva a uma perda de substrato dental causada pela sua exposição a ácidos de origem não-bacteriana. O processo se inicia com uma desmineralização superficial do esmalte, que, quando da continua exposição a soluções erosivas, pode levar a exposição do esmalte, causando problemas estéticos/funcionais aos pacientes, além de aumentar a chance de hipersensibilidade dentinária. Os produtos fluoretados, quando aplicados sobre a superfície dental, formam uma barreira física de proteção, que também pode agir como reservatório de íons F. Entretanto, frente a recorrentes desafios erosivos, esta proteção tem efetividade limitada. A literatura recente já demonstrou a capacidade de compostos contendo cátions metálicos polivalentes associados a fluoretos, incluindo o tetrafluoreto de titânio (TiF 4 ), para formar camadas mais ácido-resistentes. A capacidade do íon titânio de se ligar simultaneamente aos íons F e ao tecido dental permite a formação de uma barreira de difusão na superfície dental, conhecida como glaze, que a protege contra desmineralização ácida. Entretanto, ainda é necessário estabelecer um protocolo clínico ideal envolvendo a definição de fatores capazes de determinar o sucesso do tratamento, como concentração, pH, veículo e forma/tempo de aplicação, além da frequência para reaplicação. A presente revisão crítica tem como objetivo proporcionar uma breve visão geral dos mecanismos de ação do TiF 4 e discutir os fatores que podem melhorar sua capacidade protetora contra a erosão dental.Palavras-chave: Erosão Dentária. Flúor. Titânio.

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Root surface reactions to TiF₄and SnF₂solutions in vitro: An ultrastructural study

Cited by 14 publications

References 26 publications

Protective Effect of Different Tetrafluorides on Erosion of Pellicle-Free and Pellicle-Covered Enamel and Dentine

Protective Effect of Different Tetrafluorides on Erosion of Pellicle-Free and Pellicle-Covered Enamel and Dentine

In vitro Reduction of Dental Erosion by Low-Concentration TiF<sub>4</sub> Solutions

Titanium Tetrafluoride (TiF4) in the Treatment of Dental Erosion

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