Rosai–Dorfman disease with multi-organ involvement in head and neck region

Doença de Rosai-Dorfman como diagnóstico diferencial de lesão ulcerada de prega vocal

“…2 Published cases describe laryngeal involvement associated with lymphadenopathy or disease in other sites; 3,5 however, there are no descriptions of glottic involvement only, as in the present case. The etiology of RDD remains unclear.…”

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): clinico-pathological study of three cases

“…While the onset of SHLM may be preceded by a non-specific upper respiratory tract infection, the first manifestation is usually an asymptomatic disease [5]. Some patients may refer to an additional history of malaise, night sweats, weight loss or symptoms induced by the lymph node or extranodal tissue enlargement [15,20]. Approximately 90% of all SHLM patients have massive lymphadenopathies at presentation, but in our cases 1 and 3 these were not very large.…”

Enfermedad de Rosai-Dorfman con compromiso laríngeo: A propósito de un caso

“…El uso de corticoides sistémicos, quimioterapia, radioterapia o cirugía ha sido reportado en el caso de lesiones que podrían producir compromiso orgánico grave 21 . En el caso de lesiones que comprometen las vías respiratorias, las opciones de tratamiento han incluido la resección quirúrgica o con láser de CO 2 de las lesiones, uso de corticoides sistémicos o isotretinoína [22][23][24][25] . Sin embargo, la resección de las lesiones presenta una alta tasa de recurrencias 16 .…”