1976
DOI: 10.1128/aac.9.2.350
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Rosamicin: In Vitro Activity Against Anaerobes and Comparison with Erythromycin

Abstract: The in vitro activity of rosamicin was determined against 231 strains of anaerobic bacteria and compared with the activity of erythromycin against the same strains. Rosamicin and erythromycin had similar activity against strains of Peptostreptococcus and gram-positive nonsporeforming bacilli. Rosamicin was somewhat more active against strains of Peptococcus, Clostridium , and gram-negative anaerobes. All strains of Bacteroides fragilis tes… Show more

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Cited by 18 publications
(13 citation statements)
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“…Both compounds reportedly are effective in vitro, at physiological pH's, against most gram-positive aerobic cocci, including some resistant to erythromycin. Additionally, both have demonstrated in vitro activity against a variety of anaerobic species (7).…”
mentioning
confidence: 99%
“…Both compounds reportedly are effective in vitro, at physiological pH's, against most gram-positive aerobic cocci, including some resistant to erythromycin. Additionally, both have demonstrated in vitro activity against a variety of anaerobic species (7).…”
mentioning
confidence: 99%
“…Rosaramicin is a broad-spectrum macrolide antibiotic, similar to erythromycin (1,10). The antibiotic is isolated from fermentation broth of Micromonospora rosaria (11).…”
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confidence: 99%
“…Rosaramicin (formerly called rosamicin) is a macrolide antibiotic, chemically similar to erythromycin, and active against Bacteroides fragilis, Peptococcus, Clostridium, and some aerobes including Neisseria gonorrhoeae (5,8), Staphylococcus aureus, Staphylococcus epidermidis, viridans and group A streptococci, and enterococci (4,9,11,18). Although tetracycline is recommended for the treatment of nongonococcal urethritis (20), C. trachomatis has been found to be more susceptible to rosaramicin in vitro (16 Several strains of U. urealyticum were tested for their susceptibilities to antibiotics in vitro by Spaepen and Kundsin (17) by a direct disk elution method.…”
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confidence: 99%