“…Recently, some authors showed that instrumentation salvage is possible when techniques such as serial debridements, antibiotic medication, irrigation-suction systems and delayed primary closure of the wound are used [39,42,51,54,59,60,65]. Primary or delayed primary closure is often not possible and muscle flaps are required to close the dead space and to provide soft tissue coverage [15,27,46,63]. The muscle flaps, however, as extensive surgical procedures bear a significant morbidity for these critically ill patients [61,69].…”