Rotaviruses

Yen, Catherine; Cortese, Margaret M.

doi:10.1016/b978-0-323-40181-4.00216-4

Cited by 5 publications

(15 citation statements)

References 132 publications

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“…The airborne spread of rotavirus infection has also been hypothesized because of the short incubation period (1–3 days), rapid seasonal transmission through populations, and the massive nature of outbreaks [ 60 ]. However, this has not yet been established in humans.…”

Section: Exposure Pathways In Developing Countriesmentioning

confidence: 99%

“…Laboratory diagnosis of rotavirus infection involves testing of fresh, whole stool samples or rectal swabs from diarrheic patients for the presence of the virus, virus-specific antigen, or RNA [ 60 ]. Direct detection of rotavirus involves the use of electron microscopy (EM), a sensitive and highly specific method.…”

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

“…The latex agglutination technique is rapid and simple to carry out without sophisticated equipment, making it useful in disease outbreak detection especially in resource-poor settings where means for rotavirus recognition are in short supply [ 140 ]. Although, the ELISA-based technique is the most widely explored antigen screening platform due to its high sensitivity, specificity, and adaptability to a large sample volume of samples in the 96-well plate [ 60 ]. Growing rotavirus in cell culture helps to confirm viral viability and also improves the molecular detection of the virus, which may be present in very low concentrations in the clinical or environmental samples [ 39 ].…”

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

“…Polymerase chain reaction (PCR)-based technique (e.g., reverse transcription (RT)-PCR, qPCR, real-time PCR), which detects RNA in the clinical sample, is a more sensitive method than antigen detection platform but, to date, it remains primarily a research tool [ 60 ]. The sequencing of VP7, VP4, and other genome segments is required for genotyping circulating rotavirus strains.…”

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

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Rotaviruses: From Pathogenesis to Disease Control—A Critical Review

Omatola

Olaniran

2022

Viruses

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Since their first recognition in human cases about four decades ago, rotaviruses have remained the leading cause of acute severe dehydrating diarrhea among infants and young children worldwide. The WHO prequalification of oral rotavirus vaccines (ORV) a decade ago and its introduction in many countries have yielded a significant decline in the global burden of the disease, although not without challenges to achieving global effectiveness. Poised by the unending malady of rotavirus diarrhea and the attributable death cases in developing countries, we provide detailed insights into rotavirus biology, exposure pathways, cellular receptors and pathogenesis, host immune response, epidemiology, and vaccination. Additionally, recent developments on the various host, viral and environmental associated factors impacting ORV performance in low-and middle-income countries (LMIC) are reviewed and their significance assessed. In addition, we review the advances in nonvaccine strategies (probiotics, candidate anti-rotaviral drugs, breastfeeding) to disease prevention and management.

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Section: Exposure Pathways In Developing Countriesmentioning

confidence: 99%

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

Section: Laboratory Diagnosis Of Rotavirus Infectionmentioning

confidence: 99%

See 2 more Smart Citations

Rotaviruses: From Pathogenesis to Disease Control—A Critical Review

Omatola

Olaniran

2022

Viruses

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“…The genetic variability of the VP4 and VP7-encoding genes determines the binary RVA genotype classification system [165]. Currently, 27 G (VP7) and 37 P genotypes (VP4) of RVA have been described in mammals and avian species [166,167]. First evidence on the susceptibility of cats to feline rotavirus (FRV) infection was obtained serologically in 1978 by McNulty et al [168].…”

Section: Other Virusesmentioning

confidence: 99%

Feline Virome—A Review of Novel Enteric Viruses Detected in Cats

Martino

Profio

Melegari

et al. 2019

Viruses

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Recent advances in the diagnostic and metagenomic investigations of the feline enteric environment have allowed the identification of several novel viruses that have been associated with gastroenteritis in cats. In the last few years, noroviruses, kobuviruses, and novel parvoviruses have been repetitively detected in diarrheic cats as alone or in mixed infections with other pathogens, raising a number of questions, with particular regards to their pathogenic attitude and clinical impact. In the present article, the current available literature on novel potential feline enteric viruses is reviewed, providing a meaningful update on the etiology, epidemiologic, pathogenetic, clinical, and diagnostic aspects of the infections caused by these pathogens.

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Octupolar Plasmonic Nanosensor Based on Ordered Arrays of Triangular Au Nanopillars for Selective Rotavirus Detection

Rippa

Castagna

Brandi

et al. 2020

ACS Appl. Nano Mater.

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Technologies based on plasmonic nanostructures are a rapidly growing field that aims to be a valid alternative to conventional diagnostic tools. One of the main goals in their technological development consists of the design of systems for sensitive and specific detection of pathogens in water. Among these, rotaviruses represent the main cause of childhood viral gastroenteritis in humans. In this work, we design functionalized plasmonic label-free nanosensors based on localized surface plasmon resonance (LSPR) sensing to detect ultralow concentrations of rotavirus. We demonstrate the possibility of detecting in a specific way amounts lower than 1 × 103 plaque forming unit (PFU)/mL of the Rotavirus in water using a very low sample volume (2 μL). These results together with those obtained in our specificity tests performed with two different viruses (bovine herpesvirus, BHV1; and equine viral arteritis, EVA) confirm that our device is very promising to develop a rapid, simple, very sensitive, and specific immunoassay for detection of rotavirus. To the best of our knowledge, this is the first time that LSPR nanobiosensing has been used for the sensitive and specific detection of rotavirus.

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Rotaviruses

Cited by 5 publications

References 132 publications

Rotaviruses: From Pathogenesis to Disease Control—A Critical Review

Rotaviruses: From Pathogenesis to Disease Control—A Critical Review

Feline Virome—A Review of Novel Enteric Viruses Detected in Cats

Octupolar Plasmonic Nanosensor Based on Ordered Arrays of Triangular Au Nanopillars for Selective Rotavirus Detection

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