2013
DOI: 10.1109/tcbb.2012.103
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Rough-Fuzzy Clustering for Grouping Functionally Similar Genes from Microarray Data

Abstract: Gene expression data clustering is one of the important tasks of functional genomics as it provides a powerful tool for studying functional relationships of genes in a biological process. Identifying coexpressed groups of genes represents the basic challenge in gene clustering problem. In this regard, a gene clustering algorithm, termed as robust rough-fuzzy c-means, is proposed judiciously integrating the merits of rough sets and fuzzy sets. While the concept of lower and upper approximations of rough sets de… Show more

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Cited by 77 publications
(31 citation statements)
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“…This hybrid combination of rough fuzzy [15][16][17][18][19] clustering had applied to many of the research application areas like brain MRI [15,19], Micro gene expression data [16][17][18] and various other datasets like Synthetic dataset, Iris dataset [19]. This hybrid technique gave most significant results in almost every datasets.…”
Section: Related Workmentioning
confidence: 99%
“…This hybrid combination of rough fuzzy [15][16][17][18][19] clustering had applied to many of the research application areas like brain MRI [15,19], Micro gene expression data [16][17][18] and various other datasets like Synthetic dataset, Iris dataset [19]. This hybrid technique gave most significant results in almost every datasets.…”
Section: Related Workmentioning
confidence: 99%
“…In recent years, the theory of rough sets has gained popularity in handling uncertainties associated with incomplete class definitions. The rough-fuzzy clustering, presented in (Maji and Pal (2007); Maji and Paul (2013)), judiciously integrates the merits of fuzzy set and rough set theory. The rough-fuzzy clustering based segmentation methods (Maji and Roy (2015a,b); Maji and Pal (2007)) have shown their effectiveness in image segmentation by capturing different uncertainties that cannot be handled by traditional clustering algorithms, such as hard c-means (HCM), FCM and so on.…”
Section: Introductionmentioning
confidence: 99%
“…Aside from the above mentioned three aspects of literature, there exists a plenty of other work regarding soft-partition clustering. For example, Miyamoto and Umayahara [3,29] regarded FCM as a regularization of crisp c -means, and then via the quadratic regularization function of memberships they designed another regularization method named fuzzy clustering by quadratic regularization (FC-QR); Yu [30] devised the general c -means model by extending the definition of the mean from a statistical point of view; Gan and Wu [31] proposed a classic fuzzy subspace clustering model and further analyzed its convergence; Wang et al [32] proposed another fuzzy subspace clustering method for handling high-dimensional, sparse data; and in addition, some application studies with respect to soft-partition clustering were also conducted, such as image compression [33,34], image segmentation [35-37], real-time target tracking [38,39], and gene expression data analysis [40]. …”
Section: Introductionmentioning
confidence: 99%