2004
DOI: 10.1016/j.bone.2004.03.009
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Roughness response genes in osteoblasts

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Cited by 216 publications
(153 citation statements)
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References 27 publications
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“…Nanotechnology involves materials that have a nano-sized topography or are composed of nano-sized materials with a size range between 1 and 100 nm. Nanometer roughness plays an important role in the adsorption of proteins, adhesion of osteoblastic cells and thus the rate of osseointegration (Brett et al, 2004).…”
Section: Surface Roughnessmentioning
confidence: 99%
“…Nanotechnology involves materials that have a nano-sized topography or are composed of nano-sized materials with a size range between 1 and 100 nm. Nanometer roughness plays an important role in the adsorption of proteins, adhesion of osteoblastic cells and thus the rate of osseointegration (Brett et al, 2004).…”
Section: Surface Roughnessmentioning
confidence: 99%
“…Macro-level indeed produces favorable results in respect to primary stability; however, it is associated with ionic leakage and peri-implantitis. Nano-level has been advocated in the past few years as it encourages protein absorption and guides osteoblast adhesion to the titanium surface [73]. Achieving nano-level roughness with current technology deems difficult and expensive.…”
Section: Resultsmentioning
confidence: 99%
“…The effective surface tension, as well as the surface energy related to the topography of surface, is assumed to influence the final interactions of the implant with the surrounding environment. It is also reported that rough surfaces promote better osseointegration than smooth surfaces (Brett et al, 2004;Cochran, 1999;Jansson & Tengvall, 2004;Webster et al, 1999). Treatment of titanium surface by titanium doped hydrocarbon layer is observed to have strong influence on the adsorption of HPF molecules.…”
Section: Introductionmentioning
confidence: 92%