Roundtable discussion: Dietary fats in prevention of atherosclerotic cardiovascular disease

Severson, Tracy; Kris-Etherton, Penny M.; Robinson, Jennifer G.; Guyton, John R.

doi:10.1016/j.jacl.2018.05.006

Cited by 4 publications

(1 citation statement)

References 5 publications

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“…Unsaturation of the fatty acid backbone results in increased 3D volume. As fatty acids are constituents of phospholipid membranes, a diet rich in polyunsaturated fat leads to more voluminous, fluid and spacious cell membranes, favouring exchanges between the intracellular and extracellular compartments and reducing the risk of atherosclerosis 68 . Furthermore, the inflammatory cascade starts with the synthesis of eicosanoids, which are pro-inflammatory signalling molecules derived from PUFAs.…”

Section: Plant Fatsmentioning

confidence: 99%

Plant-based diets to manage the risks and complications of chronic kidney disease

et al. 2020

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Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus on the quantity of nutrients consumed. Without appropriate dietary counselling, these restrictions can result in a low intake of fruits and vegetables and a lack of diversity in the diet. Plant nutrients and plant-based diets could have beneficial effects in patients with CKD: increased fibre intake shifts the gut microbiota towards reduced production of uraemic toxins; plant fats, particularly olive oil, have anti-atherogenic effects; plant anions might mitigate metabolic acidosis and slow CKD progression; and as plant phosphorus has a lower bioavailability than animal phosphorus, plant-based diets might enable better control of hyperphosphataemia. Current evidence suggests that promoting the adoption of plant-based diets has few risks but potential benefits for the primary prevention of CKD, as well as for delaying progression in patients with CKD G3-5. These diets might also help to manage and prevent some of the symptoms and metabolic complications of CKD. We suggest that restriction of plant foods as a strategy to prevent hyperkalaemia or undernutrition should be individualized to avoid depriving patients with CKD of these potential beneficial effects of plant-based diets. However, research is needed to address knowledge gaps, particularly regarding the relevance and extent of diet-induced hyperkalaemia in patients undergoing dialysis.

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Section: Plant Fatsmentioning

confidence: 99%