Routine Screening for Eosinophilic Esophagitis in Patients Presenting with Dysphagia

Ricker, Jonathan; McNear, Scott; Plott, Eric; Cassidy, Timothy; Arnold, Hays; Franklin, Kevin

doi:10.14309/00000434-200910003-00022

Cited by 3 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…21,22 The peak incidence is between 20 and 40 years of age. 21 Up to 22% of patients undergoing upper endoscopy for non-obstructive dysphagia 23,24 and over 50% of patients referred for food impaction receive a diagnosis of EoE. 25,26 Most patients have co-occurring allergic rhinitis, asthma, IgE-mediated food allergies and atopic dermatitis, and children show higher hypersensitivity against food antigens.…”

Section: Introductionmentioning

confidence: 99%

Eosinophilic esophagitis: clinical, endoscopic, histologic and therapeutic differences and similarities between children and adults

Visaggi

Savarino

Sciumè

et al. 2021

Therap Adv Gastroenterol

View full text Add to dashboard Cite

In the absence of secondary causes, eosinophilic esophagitis (EoE) is a chronic, local, progressive, T-helper type 2 immune-mediated disorder characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. In the last 20 years, the incidence and prevalence of EoE have risen sharply, and the chances of encountering affected patients in clinics and endoscopy rooms have increased. Nevertheless, it is estimated that the mean diagnostic delay of EoE is 4–6 years in both children and adults. Unfortunately, the longer the disease stays unrecognized, the likelier it is for the patient to have persistent or increased esophageal eosinophilic inflammation, to complain of non-resolving symptoms, and to develop fibrotic complications. Early detection depends on the recognition of initial clinical manifestations that vary from childhood to adulthood and even among patients of the same age. The disease phenotype also influences therapeutic approaches that include drugs, dietary interventions, and esophageal dilation. We have herein reviewed epidemiologic, clinical, endoscopic, and histologic features and therapeutic options of EoE focusing on differences and similarities between children and adults that may certainly serve in daily clinical practice.

show abstract

Section: Introductionmentioning

confidence: 99%

Eosinophilic esophagitis: clinical, endoscopic, histologic and therapeutic differences and similarities between children and adults

Visaggi

Savarino

Sciumè

et al. 2021

Therap Adv Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Nearly one in four patients undergoing upper endoscopy for nonobstructive dysphagia might have eosinophilic oesophagitis (EoE). 1 Non-invasive testing in this population would offer a potentially cheaper, office-based approach to diagnosis. Alterations in the gut microbiome have been linked to the development of numerous gastrointestinal diseases.…”

Section: Editorial: Non-invasive Testing For Eoe-does Microbiome Test...mentioning

confidence: 99%

“…Nearly one in four patients undergoing upper endoscopy for non‐obstructive dysphagia might have eosinophilic oesophagitis (EoE) 1 . Non‐invasive testing in this population would offer a potentially cheaper, office‐based approach to diagnosis.…”

Section: Figurementioning

confidence: 99%

Editorial: non‐invasive testing for EoE—does microbiome testing hold the key?

Naik

Patel

2022

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…La densidad del infiltrado eosinofílico no se correlaciona con la gravedad de los síntomas (33). Un estudio reciente mostró que la EE es frecuente en pacientes con disfagia no obstructiva: en 22 de 100 pacientes con este tipo de disfagia se hizo el diagnóstico de EE, por lo que los autores propusieron la práctica rutinaria de biopsias esofágicas en todo paciente con esta forma de disfagia (34).…”

Section: Manifestaciones Clínicasunclassified

“…El diagnóstico de EE se debe plantear siempre en el paciente con disfagia, con alteraciones morfológicas del esófago o sin ellas, especialmente en niños u hombres jóvenes que tengan historia de alergias a las comidas, alergias ambientales y/o asma o atopia (34). No hay marcadores serológicos específicos de EE (1), pero se pueden encontrar niveles elevados de IgE y eosinofilia periférica, aunque esta última no está presente en todos los pacientes y si se presenta, en general es leve (44,45).…”

Section: Diagnósticounclassified

Esofagitis eosinofílica: estado actual

Muñoz-Ortiz

Baños

2012

Iatreia

View full text Add to dashboard Cite

La esofagitis eosinofílica es una infiltración del esófago por eosinófilos, presumiblemente de origen alérgico, que se presenta en niños y adultos. En estos últimos es más frecuente en hombres de edad media y su característica clínica principal es la disfagia. El conocimiento de esta enfermedad ha tenido gran desarrollo en los últimos 10 años con mejor entendimiento de su fisiopatología y con estudios que buscan evaluar diferentes alternativas de tratamiento. Se presenta una revisión de la literatura en la que se describen la epidemiología, manifestaciones clínicas, fisiopatología, diagnóstico diferencial y opciones terapéuticas de esta enfermedad.

show abstract

Routine Screening for Eosinophilic Esophagitis in Patients Presenting with Dysphagia

Cited by 3 publications

References 0 publications

Eosinophilic esophagitis: clinical, endoscopic, histologic and therapeutic differences and similarities between children and adults

Eosinophilic esophagitis: clinical, endoscopic, histologic and therapeutic differences and similarities between children and adults

Editorial: non‐invasive testing for EoE—does microbiome testing hold the key?

Esofagitis eosinofílica: estado actual

Contact Info

Product

Resources

About