2022
DOI: 10.3390/nu14194166
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Royal Jelly: Beneficial Properties and Synergistic Effects with Chemotherapeutic Drugs with Particular Emphasis in Anticancer Strategies

Abstract: Cancer is one of the major causes of death globally. Currently, various methods are used to treat cancer, including radiotherapy, surgery, and chemotherapy, all of which have serious adverse effects. A healthy lifestyle, especially a nutritional diet, plays a critical role in the treatment and prevention of many disorders, including cancer. The above notion, plus the trend in going back to nature, encourages consumers and the food industry to invest more in food products and to find potential candidates that c… Show more

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Cited by 20 publications
(17 citation statements)
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“…More specifically, RJ’s antitumor property has been researched and mechanisms such as cancer-cell multiplication, metastasis and tumorigenesis repression have been found and attributed to this bee secretion. These mechanisms are due to the restriction of angiogenesis and the ability of RJ to activate the immune system [ 78 , 86 ].…”
Section: Functional Properties Of Royal Jellymentioning
confidence: 99%
“…More specifically, RJ’s antitumor property has been researched and mechanisms such as cancer-cell multiplication, metastasis and tumorigenesis repression have been found and attributed to this bee secretion. These mechanisms are due to the restriction of angiogenesis and the ability of RJ to activate the immune system [ 78 , 86 ].…”
Section: Functional Properties Of Royal Jellymentioning
confidence: 99%
“…Thymol is among the main chemical constituents of thymus essential oils, which, when applied to other plants, can help in the reduction of bee diseases. For bees infected with nosema, candies containing 0.12 mg/g thymol can decrease bee mortality and increase bee survival [ 10 ]. Administration of syrup enriched with 1% or 10% L. nobilis leaf extracts is effective inhibiting in vivo development of nosema in bees, depending on the dosage applied.…”
Section: Safety Of Natural Products As Treatments Of Nosemosismentioning
confidence: 99%
“…They play a critical role as pollinators of agricultural crops, wild flora, and natural vegetation, and are an effective biological monitor of environmental contaminants, acting as collectors for airborne particulates and dust deposited on the surfaces on which they land. Honey bees are also source of honey, royal jelly, propolis, bee pollen, bee bread, venom, and wax [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ].…”
Section: Introductionmentioning
confidence: 99%
“…In this way, manuka honey induces apoptosis in epithelial cancer cells, and Quercus pyrenaica honeydew honey, with its high phenolic content, causes DNA damage and apoptosis in gastric adenocarcinoma cells [ 16 , 17 ]. Anticancer properties via apoptosis induction of cancer cells were also described for propolis and royal jelly [ 18 , 19 ]. Chinese propolis was shown to induce apoptosis and inhibit the proliferation of human gastric cancer cells [ 20 ].…”
Section: Introductionmentioning
confidence: 99%