RR Variability in Healthy, Middle-Aged Persons Compared With Patients With Chronic Coronary Heart Disease or Recent Acute Myocardial Infarction

Abstract

All measures of RR variability were significantly and substantially higher in healthy subjects than in patients with chronic or subacute coronary heart disease. The difference between healthy middle-aged persons and those with coronary heart disease was much greater 2 weeks after myocardial infarction than 1 year after infarction, but the fractional distribution of total power into its four component bands was similar for the healthy group and the two coronary heart disease groups. Values of RR variability previously reported to predict death in patients with known chronic coronary heart disease are rarely (approximately 1%) found in healthy middle-aged individuals. Thus, when measures of RR variability are used to screen groups of middle-aged persons to identify individuals who have substantial risk of coronary deaths or arrhythmic events, misclassification of healthy middle-aged persons should be rare.

Inflammation-related effects of adjuvant influenza A vaccination on platelet activation and cardiac autonomic function

“…Many studies have also shown that even an alteration of cardiac ANS activity towards a predominance of adrenergic tone is associated with an increased risk of cardiac events in several disease settings [9][10][11][12], including diabetes [34].…”

“…Moreover, markers of inflammation predict cardiovascular events in several disease states [4][5][6]. Increased platelet activation [7,8] and sympathovagal imbalance of cardiac autonomic nervous system (ANS) activity [9][10][11][12] are also well-known predictors of acute coronary events.…”

Efeitos da idade e da aptidão aeróbica na recuperação da frequência cardíaca em homens adultos

“…Studies have shown that there is a decrease in HRV with advancing age [2][3][4][5][6] and that this reduction is associated with the emergence or worsening of cardiovascular disease, increasing the risk of death from all causes [7][8][9][10][11] .…”

Reproducibility of heart rate variability parameters measured in healthy subjects at rest and after a postural change maneuver

“…Changes of neural heart modulation occur in several systemic diseases, such as diabetes (2)(3)(4)(5), hypertension (6), heart failure (7,8), and coronary heart disease (9,10). In such situations, HRV analysis can be used to monitor long-term changes of cardiac regulation by the autonomic nervous system.…”