2021
DOI: 10.1016/j.ijid.2021.08.050
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Rubella epidemiology in the Central African Republic, 2015-2016 and molecular characterization of virus strains from 2008-2016

Abstract: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, a… Show more

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Cited by 5 publications
(6 citation statements)
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References 32 publications
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“…Our data demonstrate that measles and rubella outbreaks in Senegal appear to have a seasonal pattern coinciding with the end of dry season, which is consistent with data throughout Africa and Asia [ 6 , 30 , 35 , 36 , 37 , 38 ] with some exceptions, including Zimbabwe and Uganda [ 18 , 38 ]. Apparent outbreaks of measles in Senegal were noted in 2010, 2016, 2019 and 2020 with most detections between January through April (peaking in March).…”
Section: Discussionsupporting
confidence: 89%
“…Our data demonstrate that measles and rubella outbreaks in Senegal appear to have a seasonal pattern coinciding with the end of dry season, which is consistent with data throughout Africa and Asia [ 6 , 30 , 35 , 36 , 37 , 38 ] with some exceptions, including Zimbabwe and Uganda [ 18 , 38 ]. Apparent outbreaks of measles in Senegal were noted in 2010, 2016, 2019 and 2020 with most detections between January through April (peaking in March).…”
Section: Discussionsupporting
confidence: 89%
“…In terms of gender distribution, the male to female ratio of rubella cases was 1.67:1, higher than the previous ratio (13), similar to that in Henan Province (10), as opposed to that in Africa (14). The incidence in males is higher than in females, which is consistent with the national study (7).…”
Section: Figuresupporting
confidence: 86%
“…21 We also observed a 12.7% prevalence for rubella, 16.4% for HHV-6% and 3.75% for parvovirus B19 indicating that clinical diagnosis is not sufficient to distinguish measles cases from other pathologies with similar symptoms. 7 Indeed, laboratory confirmation is necessary for surveillance and measles control programs. The detection of Rubella cases behind measles like symptoms is a clear warning to the Guinean authorities for the mother/fetus health.…”
Section: Discussionmentioning
confidence: 99%
“…5,6 However, other infections with a similar symptomatology such as rubella may be found and could impact the follow-up and treatment of patients. 7 This situation is specifically an issue in Guinea with recurring measles outbreaks and limited serological or molecular analysis. Moreover, because of the overcrowd in medical facilities during the epidemic, blood sampling might be tough to perform for young sick patients and often impossible for babies.…”
Section: Introductionmentioning
confidence: 99%