2002
DOI: 10.1001/jama.287.22.2968
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Rupture Rate of Large Abdominal Aortic Aneurysms in Patients Refusing or Unfit for Elective Repair

Abstract: UPTURE OF ABDOMINAL AORtic aneurysm (AAA) can be prevented by elective surgical repair, but because most AAA never rupture, 1 elective repair is reserved for patients at high risk of rupture. The most commonly used predictor of rupture is the maximum diameter of the AAA. Two randomized trials found no reduction in mortality from repairing AAA smaller than 5.5 cm in patients at low operative risk. 2,3 No randomized trials are available in patients with larger AAA, and decision making in these patients is often … Show more

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Cited by 531 publications
(253 citation statements)
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“…For AAA diameters outside that included in the RESCAN project, information on AAA growth and risk of rupture was taken from other previously published studies. [47][48][49][50] DATA SOURCES NIHR Journals Library www.journalslibrary.nihr.ac.uk…”
Section: Aneurysm Growth and Risk Of Rupturementioning
confidence: 99%
See 1 more Smart Citation
“…For AAA diameters outside that included in the RESCAN project, information on AAA growth and risk of rupture was taken from other previously published studies. [47][48][49][50] DATA SOURCES NIHR Journals Library www.journalslibrary.nihr.ac.uk…”
Section: Aneurysm Growth and Risk Of Rupturementioning
confidence: 99%
“…47 Extrapolation assumes rupture probability doubles every 0.5 cm size increase up to 6.5 cm, then switches to the given values for 7.0 cm and 8.0 cm. 49,50 The current data we use are shown in Table 19.…”
Section: Data Sources and Variable Estimationmentioning
confidence: 99%
“…About a quarter of untreated AAAs end with rupture [5], which has a mortality rate of 70–80% [6]. The risk of rupture increases with an increasing diameter of the aneurysm [7]. The epidemiological profile of AAA seems to be changing.…”
mentioning
confidence: 99%
“…39 Similarly, the 5-year overall cumulative rupture rate of incidentally diagnosed AAAs in population-based samples is 25-40% for aneurysms of > 5.0 cm diameter and 1-7% for aneurysms of 4.0-5.0 cm in diameter. 40,41 Rupture rates have been found to be doubled in current smokers compared with ex-smokers or non-smokers (p = 0.001) and to increase with mean arterial pressure (per 10 mmHg) (p = 0.001).…”
Section: Rupture Rates Of Small Abdominal Aortic Aneurysmsmentioning
confidence: 98%