In places with a predominantly natural heritage, environmental and development discourses are intertwined and often competing. A key dimension is the social construction of socio-spatial relationships, and particularly, the attribution of core and periphery features. In this article, we investigate environmental and development discourses in the peripheral spatial context of the Aysén region of Chile. Three research questions guide the investigation: (a) What are the dominant environmental and development discourses? (b) what are the main synergies and tensions among discourses? and (c) what are the (discursive) implications for (de-)peripheralization? Based on semistructured interviews and secondary sources, we identify six regional discourses on environment and development. Imaginaries of nature, regional development, and economic growth are the common denominators that create synergies and tensions. We conclude that environmental and development discourses play a key role in the transformation of geographic peripheral areas. Discursive synergies can not only reinforce but also counteract tendencies of peripheralization.