Ruthenium(II) carbonyl complexes of dehydroacetic acid thiosemicarbazone: Synthesis, structure, light emission and biological activity

Synthesis, spectral characterization and catalytic studies of new ruthenium(II) chalcone thiosemicarbazone complexes

“…A strong band observed at 1328-1343 cm -1 in the free chalcone thiosemicarbazone ligands was assigned to phenolic ν C-O stretching. This band was shifted to higher wave number (1342-1371 cm -1 ) in the spectra of the complexes due to its coordination to ruthenium ion through the oxygen atom of the phenolic group [34]. This was further supported by the disappearance of the broad ν OH band around 3400-3600 cm -1 in the complexes, indicating deprotonation of the phenolic proton prior to coordination to the ruthenium metal.…”

“…Hence, from the infrared spectroscopic data, it is inferred that the azomethine nitrogen, phenolic oxygen and thienol sulfur atoms are involved in the coordination of the chalcone thiosemicarbazone to ruthenium ion in all complexes. In addition, the appearance of a strong band at 1917-1943 cm -1 and a medium intensity band at 1000-1030 cm -1 indicate the presence of carbon monoxide and nitrogen base [34], respectively. All the other characteristic bands due to triphenylphosphine or triphenylarsine (around 1440, 1090 and 700 cm -1 ) were also present in the spectra of all complexes [17].…”

Synthesis, Spectroscopic Studies of Binuclear Ruthenium(II) Carbonyl Thiosemicarba-zone Complexes Containing PPh3/AsPh3as Co-ligands: DNA Binding/Cleavage

“…In principle, the thiosemicarbazone ligands exhibit thionethiol tautomerism, since it contains a thioamide -NH-C=S functional group. 18 The free ligands display ν (C=S) absorptions in the region 807-826 cm…”

Synthesis and Characterization of N1-Phenylhydrazine-1,2-bis(carbothioamide) and Its Evaluation for Antimicrobial, Antioxidant, and Brine Shrimp Lethality Bioassay

“…Thiosemicarbazone, a large group of thiourea derivatives, exhibits various biological activities and has therefore attracted considerable pharmaceutical interest [1]. They have been evaluated as antiviral [2], antioxidant [3], antibacterial [4,5], antitumor [6,7], anticancer [8,9], and antitubercular [10][11][12] therapeutics over the last 50 years, whose biological activities are a function of parent aldehyde or ketone moiety [13]. Thiosemicarbazones are potent intermediates for the synthesis of pharmaceutical and bioactive materials, and, thus, they are used extensively in the field of medicinal chemistry [14].…”