Ryanoids and related compounds — Isolation and characterization of 11 new minor ryanoids from the plantRyania SpeciosaVahl

Abstract

In a search for minor ryanoids from the plant Ryania Speciosa Vahl, we recently characterized 11 new members of that family of natural compounds. Most of them represent ryanodine (1) and dehydroryanodine (2) with a modified stage of oxidation in ring C. A second member of the new 4-deoxy series has been identified.Key words: minor natural ryanoids, ryanodine, dehydroryanodine, deoxyryanoids.

Extraction and determination of flubendiamide insecticide in food samples: A review

“…Ryanodine receptor-targeting insecticides (Ryanoids) are a novel class of insecticides ( Coronado et al, 1994 ; Fill and Copello, 2002 ; Lahm et al, 2005 , 2007 , 2009 ; Cordova et al, 2006 ; Li et al, 2012 , 2020 ; Pawar and Bhilave, 2020). This type of insecticide is naturally extracted from tropical South American plant (Ryania speciosa Vahl) ( Rogers et al, 1948 ; Jefferies et al, 1991 ; Ruest et al, 2002 ; Sattelle et al, 2008 ). Ryanodine receptors (RyRs) are intracellular calcium channels in insects placed in the sarcoplasmic and endoplasmic reticulum in neuromuscular tissues and they are important for the control of calcium ions release.…”

Chemical Conversion of Ryanodol to Ryanodine

“…Finally, three-step chemoselective deprotection furnished hexaol 1. The new methodology and protection tactics described here will enable generation of chemical derivatives of this exceedingly complex structure [41][42][43][44] and have further application to total syntheses of biologically active natural products with pyrrole esters. [45][46][47] …”