2009
DOI: 10.1007/s12013-009-9061-8
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S100A11: Diverse Function and Pathology Corresponding to Different Target Proteins

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Cited by 67 publications
(55 citation statements)
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“…It is noteworthy that protein S100A11, implicated as a potential biomarker of infective endocarditis, was more abundant during F. alocis monoinfection (75). S100A11 proteins are involved in endocytosis and exocytosis (76), regulation of enzyme activity, cell growth regulation, apoptosis, and inflammation (77). Periodontitis is an inflammatory disease; however, its role in other systemic inflammatory diseases is unknown.…”
Section: Discussionmentioning
confidence: 99%
“…It is noteworthy that protein S100A11, implicated as a potential biomarker of infective endocarditis, was more abundant during F. alocis monoinfection (75). S100A11 proteins are involved in endocytosis and exocytosis (76), regulation of enzyme activity, cell growth regulation, apoptosis, and inflammation (77). Periodontitis is an inflammatory disease; however, its role in other systemic inflammatory diseases is unknown.…”
Section: Discussionmentioning
confidence: 99%
“…CKS2 is a subunit of cyclin dependent kinases and has been reported to be associated with liver metastasis of colon cancer (20,21). The expression of RAN, a small GTPase, has been shown to be increased in most types of cancer (22,23) while S100A11, a member of the S100 family shows either elevated or repressed expression levels depending on cancer types (24). ECT2, a Rho guanine nucleotide exchange factor, is a protooncogene cloned based on its transforming ability in fibroblast and is involved in cytokinesis (25,26).…”
Section: Discussionmentioning
confidence: 99%
“…The expression of its gene is tightly controlled by p53, through which the p21/WAF1 protein mediates p53-dependent cell cycle G1 phase arrest, in response to a variety of stress stimuli (24,55). For example, S100A11 has been shown to be involved since TGF-β induces S100A11 gene expression and translocation into the nucleus, where it interacts with p21/WaF1 (56,57). S100A4 target genes comprise p21/WAF, Bax, thrombospondin-1 and MDM2 (16,58,59).…”
Section: +mentioning
confidence: 99%