S1283 The Impact of Social Determinants of Health on Survival and Disease Severity in Patients With Hepatocellular Carcinoma

Abstract

Resistance to third generation cephalosporins was statistically significantly higher in N-SBP compared to HA-SBP (RR52.02, p50.003, CI 1.26-3.22, I2554%) and CA-SBP (RR53.96, p, 0.00001, CI52.50-3.60, I2552%) and also between HA-SBP and CA-SBP (RR52.25,p50.002, CI51.33-3.81, I250%). (Figure ) Conclusion: Our meta-analysis demonstrated that mortality rate is higher in N-SBP compared to HA-SBP and N-SBP compared to CA-SBP. Third generation cephalosporin resistance is considerably higher in N-SBP and HA-SBP compared to CA-SBP. Lower threshold to start broad spectrum antibiotics with targeted therapy guided through culture data should be undertaken for appropriate treatment of SBP and to improve mortality in N-SBP and HA-SBP.