MRI-guidance is increasingly used for minimally-invasive procedures, such as biopsy, and requires real-time active tracking of surgical instruments. Although optical and MR-based fiducial tracking devices have been used, these systems rely on complex contact with the operator or line-of-sight access for effective operation. A more straight-forward and clinically robust method is required to allow interactive real-time slice positioning of MR scan planes during interventional procedures. This study evaluated the use of a wristwatch-mounted, low cost wireless interface device for real-time MRI guidance. The device was designed to interact with software for planning rather than instrument guidance. The wireless device was integrated with two novel, open interventional magnet systems operating at 0.17T and 0.5T and utilized a novel customized graphic user interface (GUI) to assess interventional capability.