Safety and Efficacy Evaluation of TRUE TEST Panels 1.1, 2.1, and 3.1 in Children and Adolescents

Jacob, Sharon E.; Herro, Elise M.; Sullivan, Kim; Matiz, Catalina; Eichenfield, Lawrence F.; Hamann, Carsten R.

doi:10.2310/6620.2011.11011

Cited by 42 publications

(20 citation statements)

References 5 publications

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“…Of these, some focused only on children 17 , 23 , 28 , others examined mostly children and adolescents aged up to 12 years 2 , 12 , 31 whereas another study analyzed only adolescents 15 . Others studied patients from both age groups, aged up to 19-20 1 , 3 - 11 , 13 , 14 , 16 , 18 - 22 , 24 - 27 , 29 , 30 , 32 , 33 - 35 , and tested a smaller or greater number of substances than in this study: 17 substances for children under 5 years old 11 ; a pediatric series of 30 substances 23 , 24 , 25 ; 30 substances for children under 10 years old 12 ; and series of 10 substances. 30 Other studies have used standardized series for adults 1 , 2 , 5 - 11 , 13 - 16 , 19 - 22 , 25 , 27 , 28 , 31 , 33 - 35 , with variation in the number of substances tested.…”

Section: Discussionmentioning

confidence: 99%

Patch test results in children and adolescents. Study from the Santa Casa de Belo Horizonte Dermatology Clinic, Brazil, from 2003 to 2010

Rodrigues

Goulart

2015

An. Bras. Dermatol.

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BACKGROUNDPatch testing is an efficient method to identify the allergen responsible for allergic contact dermatitis.OBJECTIVETo evaluate the results of patch tests in children and adolescents comparing these two age groups' results.METHODSCross-sectional study to assess patch test results of 125 children and adolescents aged 1-19 years, with suspected allergic contact dermatitis, in a dermatology clinic in Brazil. Two Brazilian standardized series were used.RESULTSSeventy four (59.2%) patients had "at least one positive reaction" to the patch test. Among these positive tests, 77.0% were deemed relevant. The most frequent allergens were nickel (36.8%), thimerosal (18.4%), tosylamide formaldehyde resin (6.8%), neomycin (6.4%), cobalt (4.0%) and fragrance mix I (4.0%). The most frequent positive tests came from adolescents (p=0.0014) and females (p=0.0002). There was no relevant statistical difference concerning contact sensitizations among patients with or without atopic history. However, there were significant differences regarding sensitization to nickel (p=0.029) and thimerosal (p=0.042) between the two age groups under study, while adolescents were the most affected.CONCLUSIONNickel and fragrances were the only positive (and relevant) allergens in children. Nickel and tosylamide formaldehyde resin were the most frequent and relevant allergens among adolescents.

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Section: Discussionmentioning

confidence: 99%

Patch test results in children and adolescents. Study from the Santa Casa de Belo Horizonte Dermatology Clinic, Brazil, from 2003 to 2010

Rodrigues

Goulart

2015

An. Bras. Dermatol.

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“…TRUE Test1 panels were used due to the need for consistency and precision of the amount of allergen present in the test as well as the environmental challenges especially heat, humidity and transportation issues and lack of facilities for preparing patch tests on site. TRUE Test1 panels are not routinely used in the paediatric population but Jacob et al [2] found these patch tests to be safe and efficacious in the paediatric population.…”

Section: Methodsmentioning

confidence: 99%

Patch test results in paediatric patients with atopic dermatitis in Laos

et al. 2020

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Background Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population. Objectives The aim of this study was to document common allergens in paediatric patients with atopic dermatitis attending the allergy clinic in the capital, Vientiane. Patients/Materials/Methods Fifty paediatric patients with atopic dermatitis were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4. Results Twenty-six positive patch tests were recorded on Day 4 in 15 children (30%). The most common allergens were: gold (18%), nickel (10%), formaldehyde (6%) and p-Phenylenediamine (6%). Other positive allergens were potassium dichromate (2%), cobalt dichloride (2%), Bronopol (2%), paraben mix (2%), fragrance mix 1 (2%) and neomycin (2%). The majority of the patients with positive reactions were female. Conclusions This study represents the first documented patch test results in the Lao population. It is hoped that these findings will help clinicians to advise the families of children with atopic dermatitis on common allergens to avoid and inform future work on contact dermatitis in this population.

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“…Specifically, the North American Contact Dermatitis Group (NACDG) reported 24 cases of PPT to MCI/MI in children younger than 18 years of age tested between 2005 and 2012 , the Pediatric Research Equity Act study reported four cases of children 6 to 18 years of age with a PPT to MCI/MI combination using an epicutaneous patch test (T.R.U.E. test) , Chang and Nakrani reported six children (four girls, two boys, ages 3–8 years) with ACD to MI‐containing wet wipes using an epicutaneous patch test, and Admani et al published a case report of perianal dermatitis in a 9‐year‐old boy caused by contact allergy to MI‐containing wet wipes using an epicutaneous patch test. Quenen et al , in Geneva, Switzerland, recently reported four pediatric cases of MI contact allergy and stated that “it remains underdiagnosed in the United States because it is still tested in combination with MCI”.…”

Section: Published Pediatric Patch Test Results To Methylchloroisothimentioning

confidence: 99%

Appropriate Testing of Isothiazolinones in Children

Goldenberg

Lipp

Jacob

2017

Pediatric Dermatology

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Safety and Efficacy Evaluation of TRUE TEST Panels 1.1, 2.1, and 3.1 in Children and Adolescents

Cited by 42 publications

References 5 publications

Patch test results in children and adolescents. Study from the Santa Casa de Belo Horizonte Dermatology Clinic, Brazil, from 2003 to 2010

Patch test results in children and adolescents. Study from the Santa Casa de Belo Horizonte Dermatology Clinic, Brazil, from 2003 to 2010

Patch test results in paediatric patients with atopic dermatitis in Laos

Appropriate Testing of Isothiazolinones in Children

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