Safety and Efficacy of Amnion Graft in Preventing Reformation of Intrauterine Adhesions

Meta‐analysis of the use of amniotic membrane to prevent recurrence of intrauterine adhesion after hysteroscopic adhesiolysis

“…15 The quality evaluation is shown in Figure S1. 17 Three studies reported on AFS scoring [16][17][18] ; however, two of these studies 16,17 could not be analyzed because the data did not have a normal distribution and, consequently, had no standard deviation available. 15,16,18 One study used a randomized controlled design but did not use allocation concealment or masking methods.…”

“…1). [16][17][18] When compared with before hysteroscopic adhesiolysis (Fig. [16][17][18] When compared with before hysteroscopic adhesiolysis (Fig.…”

“…Three of the four studies included in the current meta-analysis adopted the 1988 AFS classification for intrauterine adhesion [16][17][18] and quantified menstruation on the basis of the WHO pictorial blood loss assessment chart. Three of the four studies included in the current meta-analysis adopted the 1988 AFS classification for intrauterine adhesion [16][17][18] and quantified menstruation on the basis of the WHO pictorial blood loss assessment chart.…”

“…Chi 2 = 2.30, df = 2 (P = 0.32); I 2 = 13% Test for overall effect: Z = 1.06 (P = 0.29)Pen et al 2017[17] Wang et al 2016[18] Abbreviations: CI, confidence interval; df, degrees of freedom; M-H, Mantel-Haenszel.…”

Prevention of Intrauterine Adhesions

“…Peng and Xia [ 42 ] applied a fresh amnion graft after lysis of intrauterine adhesions in 34 patients with moderate or severe intrauterine adhesions. Fresh amnion was cut and placed on the surface of a 14 Fr Foley balloon with the chorion side facing outwards.…”