Safety and Efficacy of Exercise Training After Coronary Stenting in Patients With Stable Coronary Artery Disease

Soga, Yoshimitsu; Yokoi, Hiroyoshi; Amemiya, Kisaki; Iwabuchi, Masashi; Nobuyoshi, Masakiyo

doi:10.1253/circj.cj-11-0470

Cited by 11 publications

(6 citation statements)

References 26 publications

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“…Longitudinal studies have shown that increased levels of PA reduce thrombosis-related cardiovascular events, e.g., nonfatal myocardial infarctions, strokes, and mortality, in people with (252, 376,504) or without a history of CVD (279,330,496). A recent meta-analysis has concluded that moderate exercise training after successful coronary stenting, compared with control group, does not significantly change the incidence of stent thrombosis and major adverse cardiovascular events (death, myocardial infarction, stroke) for up to 3 years (1.8% vs. 2.0%, P ϭ 0.73; and 14.9% vs. 15.0%, P ϭ 0.97, respectively) but is effective in reducing unscheduled hospital visits for worsening angina (20.2% vs. 27.2%, P Ͻ 0.0001) (451). Comparisons with drugs are also difficult here, but pharmacological interventions would seem to outweigh exercise benefits.…”

Section: Exercise Vs Drugs: Thrombosismentioning

confidence: 91%

Exercise is the Real Polypill

et al. 2013

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The concept of a "polypill" is receiving growing attention to prevent cardiovascular disease. Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free intervention for which our genome has been haped over evolution. Compared with drugs, exercise is available at low cost and relatively free of adverse effects. We summarize epidemiological evidence on the preventive/therapeutic benefits of exercise and on the main biological mediators involved.

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Section: Exercise Vs Drugs: Thrombosismentioning

confidence: 91%

Exercise is the Real Polypill

et al. 2013

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“…However, these have only been done in arteries, where the effects of exercise are well studied. 10,11 Given the prior success of IVC filter deployment and retrieval in porcine models, our pilot study aimed to examine the effects of mild exercise on the IVC filter interaction with the neighboring vessel wall in a porcine model.…”

Section: Discussionmentioning

confidence: 99%

Influence of Exercise on Inferior Vena Cava Wall Interaction with Inferior Vena Cava Filters: Results of a Pilot In Vivo Porcine Study

Shahid

Nirgudkar

Chandra

et al. 2022

The Arab Journal of Interventional Radiology

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Purpose The aim of this study was to assess the effect of mild exercise on inferior vena cava (IVC) filter interaction with imaging and pathological features with the neighboring vessel wall utilizing a porcine model. Methods After Institutional Animal Care and Use Committee (IACUC) approval, retrievable Option Elite IVC filters were implanted in six Yorkshire pigs utilizing the right common femoral vein approach under general anesthesia. Group A (n = 4) pigs remained sedentary for 4 weeks. Group B (n = 2) pigs were exercised using a harness and treadmill for 10 minutes/day for 4 days/week. At approximately 4 weeks, IVC venograms were performed and the pigs were sacrificed. After laparotomy, the IVC was ligated above and below the filter, excised and fixed in formalin. Gross and histological examination of the IVC was performed. Gross images of each sample were captured before removal of the filters. One longitudinal, one tangential, and five transverse representative sections were processed for paraffin sectioning and hematoxylin and eosin slides were prepared. A pathologist examined all tissues to assess differences between normal vein, group A and group B pigs. The pathologist provided an overall assessment and representative images. Results All IVC filter implantations were technically successful without adverse effects. There was no incidence of caval thrombosis, filter strut fracture, or filter migration in either group. On gross pathological examination, IVC of the pigs in group B demonstrated more perivascular and mural fibrosis than those pigs in group A. Histopathological findings correlated with gross findings. Conclusions In this pilot study, there were no incidence of IVC filter strut fracture, penetration or IVC occlusion in sedentary or exercised pigs. However, there tended to be more perivascular and mural fibrosis on pathological examination of inferior vena cavas from exercised pigs. Further larger scale studies may employ the porcine model to further understand the role exercise may play on IVC filter and caval wall interaction.

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“…AMI is a common cardiac emergency with a high mortality rate [ 1 ]. Although PCI and drugs are currently effective in treating patients, many studies have shown that even after treatment, there is still a high risk of cardiovascular disease recurrence and death after PCI, especially within 1 year after surgery [ 26 , 27 ]. Therefore, there is considerable concern about this problem.…”

Section: Discussionmentioning

confidence: 99%

Effect of Baduanjin Sequential Therapy on the Quality of Life and Cardiac Function in Patients with AMI After PCI: A Randomized Controlled Trial

Chen

Liang

Kong

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Purpose. The purpose of this study was to examine the effects of Baduanjin sequential therapy (BST) on the quality of life and cardiac function in patients with AMI after PCI. Subjects. 96 patients with AMI after PCI were randomly assigned as subjects to two groups: BST group who received 24 weeks of BST training and control group who received no training. Methods. The methods used in this study included the changes in SF-36 subscales, the measures of left ventricular ejection fraction (LVEF), N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), the body mass index (BMI), and the abdominal circumference. Results. Of the 96 participants, 82 total patients completed the entire study. At 12 weeks, role physical and health transition of SF-36 were significantly different between the two groups, with a difference of 26.12 (95% CI, 11.59 to 40.64) in role physical and a difference of 15.94 (95% CI, 5.60 to 26.28) in health transition (p<0.05). However, there were statistically significant differences in all aspects of SF-36 between the two groups at 24 weeks (p<0.05). The BST also lowered abdominal circumference and BMI as compared with the control group. In the 24-week follow-up, a significant difference was found in the decline of the LVEF in the control group (p=0.020), while there was a nonsignificant difference in the BST group (p=0.552). Compared with the control group, the BST group reduced 50 pg/ml on the NT-pro-BNP at 24 weeks (p=0.013). The effects of BST exercise were maintained at 24 weeks after the intervention. No serious adverse events were observed. Conclusions. The BST appears to improve the quality of life in patients with AMI after PCI, with additional benefits of lowered abdominal circumference and BMI and improved level of cardiac function. This trial is registered with NCT02693795.

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Safety and Efficacy of Exercise Training After Coronary Stenting in Patients With Stable Coronary Artery Disease

Cited by 11 publications

References 26 publications

Exercise is the Real Polypill

Exercise is the Real Polypill

Influence of Exercise on Inferior Vena Cava Wall Interaction with Inferior Vena Cava Filters: Results of a Pilot In Vivo Porcine Study

Effect of Baduanjin Sequential Therapy on the Quality of Life and Cardiac Function in Patients with AMI After PCI: A Randomized Controlled Trial

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