Safety and efficacy of glycolic acid facial peel in Indian women with melasma

Javaheri, Saeid Mirzazadeh; Handa, Sanjeev; Kaur, Inderjeet; Kumar, Bhushan

doi:10.1046/j.1365-4362.2001.01149.x

Cited by 106 publications

(87 citation statements)

References 11 publications

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“…Present study results of objective assessment were in concordance with Javaheri et al study 39 . The use of alpha hydroxy acids, particularly glycolic acid, has expanded dramatically during the past decade for the treatment of skin disorders, including hyperpigmentation.…”

Section: Group I: Glycolic Acid Peel (Ga)supporting

confidence: 92%

See 1 more Smart Citation

Comparative Study of Efficacy of Glycolic Acid Peel and Intense Pulsed Light in the Treatment of Melasma

Desale¹,

Gugle²,

Kote³

et al. 2015

MVP Journal of Medical Science

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Section: Group I: Glycolic Acid Peel (Ga)supporting

confidence: 92%

“…In study done by Javaheri et al 39 total 3 peels, glycolic acid 50% in 3 weeks interval for 23 cases, there was > 50%…”

Section: Group I: Glycolic Acid Peel (Ga)mentioning

confidence: 93%

Comparative Study of Efficacy of Glycolic Acid Peel and Intense Pulsed Light in the Treatment of Melasma

Desale¹,

Gugle²,

Kote³

et al. 2015

MVP Journal of Medical Science

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“…Tyrosinase activity was inhibited. No effect on tyrosinase, TRP-1 and TRP-2 mRNA [98] Study on topical application of a 10% glycolic acid for melasma showed improvement in 91% of patients [138].…”

Section: A-hydroxyacidmentioning

confidence: 99%

The melanogenesis and mechanisms of skin‐lightening agents – existing and new approaches

Gillbro¹,

Olsson²

2011

Intern J of Cosmetic Sci

316

251

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SynopsisSkin-lightening products are commercially available for cosmetic purposes to obtain lighter skin complexion. Clinically, they are also used for treatment of hyperpigmentary disorders such as melasma, café au lait spot and solar lentigo. All of these target naturally melanin production, and many of the commonly used agents are known as competitive inhibitors of tyrosinase, one of the key enzymes in melanogenesis. In this review, we present an overview of commonly used skin-whitening ingredients that are commercialized, but we also hypothesize on other mechanisms that could be important targets to control skin pigmentation such as for example regulation of the adrenergic and glutaminergic signalling and also control of tetrahydrobiopterins in the human skin. Ré suméLes produits éclaircissants sont disponibles dans le commerce pour des buts cosmétiques afin d'obtenir un tient plus clair. Ils sont égale-ment utilisés en clinique, pour le traitement de troubles hyper pigmentaires comme le melasma, les taches café au lait et le lentigo solaire. Tous ces produits ont pour cible la production naturelle de mélanine et beaucoup de ceux généralement utilisés sont reconnus comme des inhibiteurs compétitifs de la tyrosinase, une des enzymes clés de la mélanogénèse. Dans cette revue, nous présentons une vue d'ensemble des ingrédients généralement utilisés et commercialisés comme blanchissant cutanés mais nous formulons aussi l'hypothèse que d'autres mécanismes pourraient être des cibles importantes pour contrôler la pigmentation de la peau comme par exemple la régula-tion du signal adrénergique et glutaminergique ou le contrôle des tetrahydrobiopterines dans la peau humaine.

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“…Some studies showed that the level of skin damage with glycolic acid peel increases is time related. The most used protocols include 5-6 of 70% glycolic acid sessions every 2 weeks [30,31].…”

Section: Glycolic Acidmentioning

confidence: 99%

The Management of Atrophic Acne Scars: Overview and New Tools

Fabbrocini¹

2013

J Clin Exp Dermatol Res

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Safety and efficacy of glycolic acid facial peel in Indian women with melasma

Abstract: The prepeel program followed by 50% glycolic acid facial peel once per month for three consecutive months proved to be an effective treatment modality in Indian patients without any significant side-effects.

Cited by 106 publications

References 11 publications

Comparative Study of Efficacy of Glycolic Acid Peel and Intense Pulsed Light in the Treatment of Melasma

Comparative Study of Efficacy of Glycolic Acid Peel and Intense Pulsed Light in the Treatment of Melasma

The melanogenesis and mechanisms of skin‐lightening agents – existing and new approaches

The Management of Atrophic Acne Scars: Overview and New Tools

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