1993
DOI: 10.1016/0002-9149(93)90026-9
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Safety and efficacy of oral sotalol for sustained ventricular tachyarrhythmias refractory to other antiarrhythmic agents

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Cited by 43 publications
(14 citation statements)
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“…Seventy per cent of the patient population of this study were the cases with sustained ventricular tachycardia, with a low prevalence (7%) of patients with aborted sudden death. This patient population is, therefore, quite different from the population enrolled in other studies dealing with ICD treatment [4,-6,26,28] or exclusively with patients with aborted sudden death [1] or dealing with primary prevention of sudden death in coronary artery disease patients at high risk [24,27] . Thus, the clinical profile of the patients enrolled in this study is similar to that of patients enrolled in the studies by Steinbeck et al [2] , by Haverkamp et al [19] and in the ESVEM study [3,11] .…”
Section: Discussionmentioning
confidence: 94%
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“…Seventy per cent of the patient population of this study were the cases with sustained ventricular tachycardia, with a low prevalence (7%) of patients with aborted sudden death. This patient population is, therefore, quite different from the population enrolled in other studies dealing with ICD treatment [4,-6,26,28] or exclusively with patients with aborted sudden death [1] or dealing with primary prevention of sudden death in coronary artery disease patients at high risk [24,27] . Thus, the clinical profile of the patients enrolled in this study is similar to that of patients enrolled in the studies by Steinbeck et al [2] , by Haverkamp et al [19] and in the ESVEM study [3,11] .…”
Section: Discussionmentioning
confidence: 94%
“…Steinbeck et al [2] , 1992 Kehoe et al [24] , 1993 473 Pacifico et al [26] , 1999 302 with ICD R to sotalol (151) or placebo (151) Prior MI in 66-73%…”
Section: Dofetilide Vs Sotalol In Isvt and Ihd 2187mentioning
confidence: 99%
“…Sotalol is safe and generally well tolerated; most of the adverse effects experienced with its use are related to its /^-blocking activity. However, sotalol has been associated with life-threatening proarrhythmias, including torsade de pointes, although the incidence of this adverse effect is low, varying between 1.8 and 3% in the clinical trials conducted to date [1][2][3]. To our knowledge, the occurrence of sotalol-induced torsade de pointes has never been reported before in haemodialysis (HD) patients.…”
Section: Introductionmentioning
confidence: 97%
“…Sotalol has been previously implicated as a cause of torsades de pointes. Kehoe et al reported 481 patients on sotalol of whom 31 (6.4%) developed some pro‐arrhythmia of which 15 (3.1%) were torsades de pointes 16 . MacNeil et al in their meta‐analysis of 3257 patients on sotalol reported torsades de pointes as occurring in 78 (2.4%) 17 .…”
Section: Discussionmentioning
confidence: 99%