Safety and Efficacy of Two Ocular Anesthetic Methods for Phacoemulsification: Topical Anesthesia and Viscoanesthesia (Visthesia™)

Perone, Jean‐Marc; Popovici, A; Ouled-Moussa, R.; Herasymyuk, O.; Reynders, Sofie

doi:10.1177/112067210701700204

Cited by 19 publications

(22 citation statements)

References 34 publications

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“…There are only two published clinical studies of viscoanaesthesia in cataract surgery patients (Poyales‐Galan & Pirazzoli 2005; Perone et al. 2007).…”

Section: Discussionmentioning

confidence: 99%

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Viscoanaesthesia in cataract surgery: a prospective, randomized clinical trial

Välimäki

Törnblom

2009

Acta Ophthalmologica

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. Purpose: We aimed to compare viscoanaesthesia (VisThesia) with intracameral lidocaine in cataract surgery carried out under topical anaesthesia. Methods: In this prospective study 98 patients were randomly assigned to receive VisThesia (group 1, n = 49) or 0.5 cc of 1% unpreserved lidocaine (group 2, n = 49). All surgery was carried out by one surgeon using clear corneal technique. Pachymetry, the status of the cornea and anterior chamber, and intraocular pressure (IOP) were checked pre‐ and postoperatively. Results: Mean pain scores were 0.12 (maximum: 3) in group 1 and 0.37 in group 2; the difference between the groups was not statistically significant (95% confidence interval [CI] 0.003−0.487; p = 0.05). A total of 48 patients in group 1 (98%) and 49 in group 2 (100%) reported no discomfort or only mild discomfort. No significant differences in flare and cells in the anterior chamber or IOP were found between the two study groups. There was a significantly greater frequency of corneal oedema in group 1 (p = 0.001). Postoperative central corneal thickness values were also significantly higher in group 1 (95% CI 11.64−57.24; p = 0.003). Conclusions: Results suggest that viscoanaesthesia provides a level of comfort during cataract surgery under topical anaesthesia similar to that facilitated by intracameral lidocaine. However, patients who are given viscoanaesthesia may have increased risk for postoperative corneal oedema.

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“…There are only two published clinical studies of viscoanaesthesia in cataract surgery patients (Poyales‐Galan & Pirazzoli 2005; Perone et al. 2007).…”

Section: Discussionmentioning

confidence: 99%

“…Although viscoanaesthesia has been shown to provide similar pain relief to topical anaesthesia without intracameral lidocaine (Perone et al. 2007), we know of no studies comparing viscoanaesthesia with intracameral lidocaine.…”

Section: Introductionmentioning

confidence: 99%

Viscoanaesthesia in cataract surgery: a prospective, randomized clinical trial

Välimäki

Törnblom

2009

Acta Ophthalmologica

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“…Despite these results, studies comparing mean ECL of patients who received viscous-dispersive OVDs versus those who received soft-shell technique (N ¼ 50 eyes, viscous-dispersive: 5%; N ¼ 50 eyes, soft-shell technique: 4.11%) and cohesive OVDs (N ¼ 123 eyes, viscous dispersive: 6.4%; N ¼ 116 eyes, cohesive: 8.8%) during phacoemulsification showed no significant difference in ECL between groups at 3 months follow-up [46,47]. One study concluded that ECL rates with the combination device were comparable to those reported for similar OVDs, whereas another study found significantly higher ECL with the combination device when compared with the use of a dispersive OVD at the beginning of surgery and a cohesive OVD prior to intraocular implantation [48,49]. Earlier studies reported varying results in ECL with this combination device.…”

Section: Ophthalmic Viscoelastic Devicesmentioning

confidence: 96%

Advances in cataract surgery

Afshari

2015

Current Opinion in Ophthalmology

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Newly emerging cataract surgical techniques cause comparable ECL to that of conventional phacoemulsification. Femtosecond laser-assistance may reduce ECL, but likely only in the early postoperative period. Further studies are needed to better elucidate short and long-term effects of FLACS on the corneal endothelium. Viscous dispersives may offer equal or increased protection of the corneal endothelium during surgery compared with viscoelastic devices currently in wide use, but further studies are required to support these results.

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“…The 0.4% ophthalmic solution was used for many years in the United States, but this compound is currently only available in combination with a vital dye, such as sodium fluorescein or disodium fluorexon, for use in applanation tonometry . Oxybuprocaine hydrochloride 0.4% ophthalmic solution is still routinely used in Europe for ophthalmic diagnostic and surgical procedures in human, and veterinary ophthalmology . To our knowledge, there have not been any published data documenting its effects on the corneal sensitivity in cats.…”

Section: Introductionmentioning

confidence: 99%