2014
DOI: 10.4161/hv.29403
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Safety and Immunogenicity of purified chick embryo cell rabies vaccine (VaxiRab N) administered intradermally as post exposure prophylaxis

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Cited by 6 publications
(8 citation statements)
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“…Across the studies identified for this review, there were 54 reports of immune responses to vaccination including healthy volunteers, or individuals at risk such as those occupationally exposed to rabies cases, and bite cases. Our analysis showed that in almost all individuals, 14 days after starting the vaccine regime, PCECV elicited RVNA titers above the WHO recommended serological threshold for an adequate immune response to vaccination (≥0.5 IU/mL serum) [7]. The studies reviewed showed that if administered promptly within a PEP protocol, PCECV with potency ≥2.5 IU per dose by the IM route or the ID route should be entirely effective in preventing rabies.…”
Section: Discussionmentioning
confidence: 78%
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“…Across the studies identified for this review, there were 54 reports of immune responses to vaccination including healthy volunteers, or individuals at risk such as those occupationally exposed to rabies cases, and bite cases. Our analysis showed that in almost all individuals, 14 days after starting the vaccine regime, PCECV elicited RVNA titers above the WHO recommended serological threshold for an adequate immune response to vaccination (≥0.5 IU/mL serum) [7]. The studies reviewed showed that if administered promptly within a PEP protocol, PCECV with potency ≥2.5 IU per dose by the IM route or the ID route should be entirely effective in preventing rabies.…”
Section: Discussionmentioning
confidence: 78%
“…The majority of intervention studies were conducted in Asia (China, India, Philippines, Thailand) [7,9,10, and eight studies in Europe (Austria, Croatia, Czech Republic, Germany, Lithuania, Serbia) [8,[41][42][43][44][45][46][47]. All the observational studies were conducted in Asian countries [19,[48][49][50][51][52][53][54][55][56][57][58][59][60][61]].…”
Section: Search Resultsmentioning
confidence: 99%
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