Safety of adjuvant intensity-modulated postoperative radiation therapy in endometrial cancer: Clinical data and dosimetric parameters according to the International Commission on Radiation Units (ICRU) 83 report

Cordoba, Abel; Nickers, Philippe; Tresch, Emmanuelle; Castelain, B.; Leblanc, Éric; Narducci, Fabrice; Tinier, F. Le; Lesoin, A.; Lacornerie, T.; Lartigau, Éric

doi:10.1016/j.rpor.2015.06.002

Cited by 2 publications

(2 citation statements)

References 35 publications

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“…7,8 Studies have suggested significantly lower rates of acute and late toxicity using postoperative pelvic IMRT. [9][10][11][12] IMRT compared to 3D planning is currently being studied in an ongoing clinical trial (RTOG 1203).…”

Section: Introductionmentioning

confidence: 99%

Should we customize PTV expansions for BMI? Daily cone beam computerized tomography to assess organ motion in postoperative endometrial and cervical cancer patients

Amini

DeWitt

Vinogradskiy

et al. 2016

Reports of Practical Oncology & Radiotherapy

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Section: Introductionmentioning

confidence: 99%

Should we customize PTV expansions for BMI? Daily cone beam computerized tomography to assess organ motion in postoperative endometrial and cervical cancer patients

Amini

DeWitt

Vinogradskiy

et al. 2016

Reports of Practical Oncology & Radiotherapy

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“…The calculated and reconstructed doses were compared by determining the differences in DVH metrics. Recommendations of the International Commission on Radiation Units and Measurements (ICRU) report 83 were used to extract evaluation parameters for PTVs (D 98 , D 2 , D 50 , and D mean ) and maximum/mean doses (D max /D mean ) for OARs, in which D 2 is recommended to represent the approximate maximum dose for tandem OARs 27 . D 98 , D 2 , and D 50 are the doses covering 98%, 2%, and 50% of the PTVs/OARs volume 28,29 , respectively.…”

Section: Compass Reconstructionmentioning

confidence: 99%

Application of a linear interpolation algorithm in radiation therapy dosimetry for 3D dose point acquisition

Yixiao

et al. 2023

Sci Rep

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Air-vented ion chambers are generally used in radiation therapy dosimetry to determine the absorbed radiation dose with superior precision. However, in ion chamber detector arrays, the number of array elements and their spacing do not provide sufficient spatial sampling, which can be overcome by interpolating measured data. Herein, we investigated the potential principle of the linear interpolation algorithm in volumetric dose reconstruction based on computed tomography images in the volumetric modulated arc therapy (VMAT) technique and evaluated how the ion chamber spacing and anatomical mass density affect the accuracy of interpolating new data points. Plane measurement doses on 83 VMAT treatment plans at different anatomical sites were acquired using Octavius 729, Octavius1500, and MatriXX ion chamber detector arrays, followed by the linear interpolation to reconstruct volumetric doses. Dosimetric differences in planning target volumes (PTVs) and organs at risk (OARs) between treatment planning system and reconstruction were evaluated by dose volume histogram metrics. The average percentage dose deviations in the mean dose (Dmean) of PTVs reconstructed by 729 and 1500 arrays ranged from 4.7 to 7.3% and from 1.5 to 2.3%, while the maximum dose (Dmax) counterparts ranged from 2.3 to 5.5% and from 1.6 to 7.6%, respectively. The average percentage dose/volume deviations of mixed PTVs and OARs in the abdomen/gastric and pelvic sites were 7.6%, 3.5%, and 7.2%, while mediastinum and lung plans showed slightly larger values of 8.7%, 5.1%, and 8.9% for 729, 1500, and MatriXX detector arrays, respectively. Our findings indicated that the smaller the spacing between neighbouring detectors and the more ion chambers present, the smaller the error in interpolating new data points. Anatomical regions with small local mass density inhomogeneity were associated with superior dose reconstruction. Given a large mass density difference in the various human anatomical structures and the characteristics of the linear interpolation algorithm, we suggest that an alternative data interpolation method should be used in radiotherapy dosimetry.

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Safety of adjuvant intensity-modulated postoperative radiation therapy in endometrial cancer: Clinical data and dosimetric parameters according to the International Commission on Radiation Units (ICRU) 83 report

Abstract: IMRT Endometrial cancerBackground: IMRT in gynecological malignancies provides excellent dosimetric data, lower

Cited by 2 publications

References 35 publications

Should we customize PTV expansions for BMI? Daily cone beam computerized tomography to assess organ motion in postoperative endometrial and cervical cancer patients

Should we customize PTV expansions for BMI? Daily cone beam computerized tomography to assess organ motion in postoperative endometrial and cervical cancer patients

Application of a linear interpolation algorithm in radiation therapy dosimetry for 3D dose point acquisition

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