“…This observation may be valid for both innate and adaptive immune responses. Reduced levels of some antimicrobial peptides, components of innate immune response, are associated with caries in childhood (Davidopoulou et al, 2012;Tao et al, 2005). The action of salivary IgA against specific surface proteins of cariogenic bacteria such as S. mutans has been the subject of many studies (Nogueira et al, 2007(Nogueira et al, , 2005Parisotto et al, 2011), with focus on GbpB and Gtf expression.…”