Salivary SARS-CoV-2 antibody detection using S1-RBD protein-immobilized 3D melt electrowritten poly(ε-caprolactone) scaffolds

Han, Pingping; Li, Chun; Staples, Reuben; Moran, Corey S.; Ramachandra, Srinivas Sulugodu; Gómez-Cerezo, Maria Natividad; Ivanovski, Sašo

doi:10.1039/d2ra03979f

Cited by 8 publications

(3 citation statements)

References 55 publications

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“…Poly-ε-caprolactone (PCL) − is a commercially available and popular material because of its biodegradable property, and it can be used to replace petrochemical plastics to solve environmental pollution caused by discarded plastic waste with slow decomposition naturally. − In addition, PCL-based biomaterials with biocompatibility − and permeability can be used in various fields. − The Lewis acidic-catalyzed ring-opening polymerization (ROP) of ε-caprolactone (CL) − is a primary method for manufacturing PCL. Al complexes are useful catalysts with a high catalytic conversion of CL polymerization, and various types of ligands, such as O,O type (diphenolate − ), N,O type (Schiff base − and aminophenolate − ), N,S type (thio-Schiff base), and N,N type (β-diketiminate − and anilido-pyrazolate), were used to synthesize Al catalysts for CL polymerization.…”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Aluminum Complexes Bearing N,N′-Diaryldioxalamidate and N,N′-Diaryldithiooxalamidate Ligands in Ring-Opening Polymerization of ε-Caprolactone

Ganta,

Chang,

Chen

et al. 2023

Organometallics

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A series of Al catalysts with N,N′-diaryloxalamidate and N,N′-diaryldithiooxalamidate ligands were synthesized, and their εcaprolactone polymerization rates were determined in this study. Of the Al complexes bearing N,N′-diaryldithiooxalamidate, [Ph H NCS] 2 Al 2 Me 4 exhibited the highest catalytic activity (conv. of poly-ε-caprolactone = 94%; [ε-caprolactone]:[[Ph H NCS] 2 Al 2 Me 4 ]:[benzyl alcohol] = 100:0.5:2 with [ε-caprolactone] = 2 M at 25 °C after 20 min), and of the Al complexes bearing N,N′-diaryldioxalamidate, [Ph H NCO] 2 Al 2 Me 4 exhibited the highest catalytic activity (conv. of poly-ε-caprolactone = 94%; [εcaprolactone]:[O H Al 2 Me 4 ]:[benzyl alcohol] = 100:0.5:2 with [ε-caprolactone] = 2 M at 25 °C after 30 min). The Al complexes bearing N,N′diaryldithiooxalamidate demonstrated a greater catalytic activity (1.4−7.3fold) than Al complexes bearing N,N′-diaryldioxalamidate. Density functional theory calculations revealed that [Ph iPr NCS] 2 Al 2 (OMe) 4 with a weaker Al−OMe bond and less repulsion of the highest transition state TS1 revealed the lower potential energy of TS1 compared to [Ph iPr NCO] 2 Al 2 (OMe) 4 and further exhibited a higher polymerization rate than [Ph iPr NCO] 2 Al 2 (OMe) 4 .

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Section: Introductionmentioning

confidence: 99%

Comparative Study of Aluminum Complexes Bearing N,N′-Diaryldioxalamidate and N,N′-Diaryldithiooxalamidate Ligands in Ring-Opening Polymerization of ε-Caprolactone

Ganta,

Chang,

Chen

et al. 2023

Organometallics

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“…To resolve this problem, biodegradable plastics, such as poly-ε-caprolactone (PCL), 2 have been designed. PCL-based biomaterials can be used in various fields 3 because of their biocompatibility 4 and permeability. 5 The primary method for PCL synthesis involves the ring-opening polymerization (ROP) of ε-caprolactone (CL) 6 by using metal complexes as catalysts.…”

Section: Introductionmentioning

confidence: 99%

Improvement of catalytic activity of aluminum complexes for the ring-opening polymerization of ε-caprolactone: aluminum thioamidate and thioureidate systems

Ganta,

Teja,

Chang

et al. 2023

Dalton Trans.

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“…Using biodegradable plastics such as poly-ε-caprolactone (PCL) may help reduce pollution. PCL-based biomaterials with biocompatibility and permeability can be used in various fields . Metal catalysts are commonly employed in the ring-opening polymerization (ROP) of ε-caprolactone (CL) for the production of PCL, and aluminum complexes serving as a strong catalyst due to their robust catalytic activities and simple synthesis.…”

Section: Introductionmentioning

confidence: 99%

Effects of Aluminum Complexes Bearing β-Thioketiminate and β-Ketiminates on ε-Caprolactone Ring-Opening Polymerization Reactivity

Ganta,

Teja,

Kamaraj

et al. 2023

Organometallics

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In this study, a series of Al complexes bearing β-ketiminates and βthioketiminates were synthesized and used as catalysts in ε-caprolactone (CL) polymerization. S Pr −Al had the highest catalytic activity among all Al complexes bearing β-thioketiminates and was more active than O Pr −Al (2.8 times as high for CL polymerization) ([CL]/[S Pr −Al]/[BnOH] = 100:1:2, [S Pr −Al] = 0.02 M, conversion = 96% after 20 min at 25 °C). All Al complexes bearing βthioketiminates exhibited higher catalytic activity (2.1-to 24.9-fold) relative to βketiminates. The polymerization results demonstrated that swapping oxygen atoms for sulfur atoms in β-ketiminate-associated Al complexes improved the catalytic activity of Al complexes for CL ROP.

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Salivary SARS-CoV-2 antibody detection using S1-RBD protein-immobilized 3D melt electrowritten poly(ε-caprolactone) scaffolds

Abstract: Our work developed a 3D SARS-CoV-2 antibody detection platform in non-invasive saliva samples using S1-RBD protein-immobilized 3D melt electrowritten poly(ε-caprolactone) scaffolds.

Cited by 8 publications

References 55 publications

Comparative Study of Aluminum Complexes Bearing N,N′-Diaryldioxalamidate and N,N′-Diaryldithiooxalamidate Ligands in Ring-Opening Polymerization of ε-Caprolactone

Comparative Study of Aluminum Complexes Bearing N,N′-Diaryldioxalamidate and N,N′-Diaryldithiooxalamidate Ligands in Ring-Opening Polymerization of ε-Caprolactone

Improvement of catalytic activity of aluminum complexes for the ring-opening polymerization of ε-caprolactone: aluminum thioamidate and thioureidate systems

Effects of Aluminum Complexes Bearing β-Thioketiminate and β-Ketiminates on ε-Caprolactone Ring-Opening Polymerization Reactivity

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