Salting effect on the liquid–liquid equilibria for the ternary system water+N-methyl-2-pyrrolidone+1-pentanol

Liquid−Liquid Equilibria for the Quaternary Systems of Water + Dimethyl Sulfoxide + 1-Pentanol + NaBr or + KBr

“…In the jacketed equilibrium glass cell (internal volume about 30 cm 3 ), the thermostatic water is circulated to control the temperature of the cell within ( 0.1 K. The cell temperature was measured by a precision thermometer (model-1506, Hart Scientific, USA) with a platinum RTD probe to an uncertainty of ( 0.03 K. In this paper, the detailed procedure of LLE data measurements and analyses or the validity test of our experimental procedure has been described elsewhere. 1,2 Five samples were replicated for each phase at a fixed experimental condition. The composition of salt in each phase was determined gravimetrically by transferring a liquid sample (about 1∼2 cm 3 ) onto watch glasses and drying in a vacuum oven at a temperature of 393.15 K for about 12 h until the weight of salt remained constant.…”

Process Modeling, Simulation, and Technoeconomic Evaluation of Separation Solvents for the Continuous Pharmaceutical Manufacturing (CPM) of Diphenhydramine

“…Experimental data for the ternary systems NMP + water + carbon tetrachloride, isobutanol, 1-pentanol, and 1-hexanol are available. 79,80 Carbon tetrachloride is strictly controlled by regulatory bodies due to its toxicity and inherent environmental hazard potential and is not considered here. 81 Isobutanol, 1-pentanol, and 1-hexanol have narrow regions of immiscibility and have been not considered suitable for application.…”

“…Published liquid–liquid equilibria for the ternary systems containing dichloromethane and chloroform are used here, as the lack of required interaction parameters for both UNIFAC and NRTL models makes theoretical modeling unavailable. Experimental data for the ternary systems NMP + water + carbon tetrachloride, isobutanol, 1-pentanol, and 1-hexanol are available. , Carbon tetrachloride is strictly controlled by regulatory bodies due to its toxicity and inherent environmental hazard potential and is not considered here . Isobutanol, 1-pentanol, and 1-hexanol have narrow regions of immiscibility and have been not considered suitable for application.…”

Salt Effect on the Isobaric Vapor–Liquid Equilibrium Study of Binary Mixtures H2O–NMP (N-Methyl-2-pyrrolidone)

“…The liquid-phase splitting for a ternary system of water + NMP + 1-pentanol can be enhanced by adding the same percentage of salts (sodium chloride, potassium chloride, or potassium acetate) and the influence follows the order of sodium chloride > potassium chloride > potassium acetate. 25 As far as we know, the salt (lithium chloride and sodium chloride) effect on isobaric VLE for the system of NMP + water has not been reported.…”

“…The liquid-phase splitting for a ternary system of water + NMP + 1-pentanol can be enhanced by adding the same percentage of salts (sodium chloride, potassium chloride, or potassium acetate) and the influence follows the order of sodium chloride > potassium chloride > potassium acetate. 25 As far as we know, the salt (lithium chloride and sodium chloride) effect on isobaric VLE for the system of NMP + water has not been reported. In this study, the isobaric vapor−liquid equilibrium data for the systems water + NMP, water + NMP + lithium chloride, and water + NMP + sodium chloride were determined at 101.3 kPa, and the thermodynamic consistency of the measured VLE data was checked by the van Ness test.…”