“…The breakage of metallic osteosynthesis devices in clinical use, namely, bone plates [11,12,13], intramedullary nail rods [14,15,16,17,18,19], spinal rods [20,21], compression hip screws (CHSs) [22], short femoral nails [23,24,25,26,27,28,29], and metaphyseal plates [22,30], due to fatigue fracture in the stress concentration region has been reported. In particular, the stress concentration region around a hole leads to crack initiation, resulting in fatigue fracture.…”