Sarcoidosis, Thyroiditis, and Addison's Disease

Karlish, A. J.; Macgregor, GeraldA.

doi:10.1016/s0140-6736(70)92871-0

Cited by 118 publications

(37 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this case report, we showed that adrenocortical insufficiency was caused by sarcoidosis involving the adrenal glands, as possible causes of Addison's disease other than sarcoidosis (11,12,(14)(15)(16) were excluded; that is, autoimmune adrenalitis, infections with tuberculosis, fungi or HIV and metastasis of carcinoma were ruled out based on the clinical findings and laboratory data. It has been shown that the onset of adrenocortical insufficiency in patients with sarcoidosis is most likely due to an autoimmune endocrine disease, autoimmune polyglandular syndrome type II (Schmidt syndrome) (17,18). However, autoimmune polyglandular syndrome type II was ruled out in this case according to the absence of anti-adrenocortical antibodies and the normal thyroid function.…”

Section: Discussionmentioning

confidence: 80%

Sarcoidosis Presenting Addison's Disease

et al. 2016

View full text Add to dashboard Cite

We herein describe a second Japanese case of sarcoidosis presenting Addison's disease. A 52-year-old man was diagnosed with sarcoidosis based on clinical and laboratory findings, including bilateral hilar lymphadenopathy and elevated levels of serum angiotensin-converting enzyme and lysozyme, as well as the presence of noncaseating epithelioid granulomas. The patient also exhibited general fatigue, pigmentation, weight loss, hypotension and hyponatremia, suggestive of chronic adrenocortical insufficiency. An endocrine examination confirmed primary adrenocortical insufficiency. This case suggests the direct involvement of sarcoid granuloma in the adrenal glands.

show abstract

Section: Discussionmentioning

confidence: 80%

Sarcoidosis Presenting Addison's Disease

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Taking into consideration that our patient had autoimmune thyroiditis and vitiligo, we believe that she should be monitored for diabetes mellitus, since by some authors sarcoidosis can be related to various polyglandular autoimmune syndromes (6,14,15).…”

Section: Discussionmentioning

confidence: 94%

Cutaneous Sarcoidosis Associated with Vitiligo and Autoimmune Thyroiditis – a Case Report

Lalošević

Škiljević

2014

Serbian Journal of Dermatology and Venereology

View full text Add to dashboard Cite

Sarcoidosis is a multisystem granulomatous disease and approximately one third of patients with the systemic form develop skin lesions. We present a case of cutaneous sarcoidosis associated with autoimmune thyroiditis and vitiligo. Although this association is rare by itself, it imposes the theory of autoimmune etiology of sarcoidosis. Moreover, our patient presented with elevated levels of serum chitotriosidase, a known biomarker in the activity of systemic sarcoidosis. To the best of our knowledge, there are no reports of chitotriosidase in isolated cutaneous sarcoidosis, raising a possible field for future research.

show abstract

“…In 1974, Bara et al ( 1 1) firstreported a case ofsarcoidosis coexisting with PSS, and Wiesenhutter and Sharma (12) reported three cases with PSS and one case with SLE,with a review of the literature, and Maekawaand Nogami (9) reported one case of PSS and sarcoidosis with esophageal adenocarcinoma. Somecase reports have discussed sarcoidosis coexisting with autoimmune diseases such as Hashimoto's thyroiditis, idiopathic thrombocytopenia, and rheumatoid arthritis (3)(4)(5)(6)(7)(8). However, the coexistence of sarcoidosis and connective diseases seems to be rare.…”

Section: Discussionmentioning

confidence: 99%

“…Not only progressive systemic sclerosis (PSS), but also Hashimoto's thyroiditis, idiopathic thrombocytopenia, rheumatoid arthritis , and other autoimmune disorders are reported to exist with sarcoidosis (3)(4)(5)(6)(7)(8)(9). Here, we describe a patient with interstitial pneumonia associated with PSS.…”

Section: Introductionmentioning

confidence: 99%