Sarcome d’Ewing à localisation cutanée primitive

A peculiar case of large primary cutaneous Ewing’s sarcoma of the foot: Case report and review of the literature

“…Shingde et al [12] and Machado et al [1] reported 7 cases and 6 cases respectively; every study observed one case of small tumor of the foot (size, not available and 5 cm, respectively). Kourda et al [13] described a single case of cutaneous ES of the foot with a diameter of 3.5 cm (data summarized in Table 1 ).…”

Extraosseous Ewing’s Tumor of Lateral Abdominal Wall

“…5 The histological image of cutaneous or subcutaneous ES is a small blue round cell with a scanty cytoplasm, and it is often confused with other skin tumors. 6 The markers are of great importance for establishing the differential diagnosis with other entities. 7 Negative leukocyte common antigen (LCA), CD30, myosin, actin, myoglobulin, neurofilament, neuron-specific enolase and S-100 protein can exclude lymphoblastic lymphoma, rhabdomyosarcoma and neuroblastoma.…”

“…9 Treatment for cutaneous Ewing's sarcoma, though not codified, consists of surgery associated with polychemotherapy and/or radiotherapy. 2,6 The current view is that surgical resection should be performed if the tumor can be completely resected. A local wide resection is the recommended operation, with the goal of a complete resection of tumor lesions and negative surgical margin, and the extent should include a 2–3 cm normal tissue surrounding the tumor if possible.…”

Primary Subcutaneous Ewing Sarcoma Presented as Pseudo Aneurysmal Subcutaneous Tumor

“…The cells are usually periodic acid-Schiff (PAS)-positive, indicating the presence of glycogen granules [ 2 ]. Characteristically, the tumor cells were positive for CD99 (MIC2 gene product), ß2 microglobulin, FLI-1 gene product and vimentin [ 3 ]. Cutaneous or subcutaneous ES should be differentiated from the other small round cell tumors of the skin such as lymphoblastic lymphoma, Merkel cell carcinoma and basaloid cell tumors, which are commonly seen in the skin (such as carcinomas of appendageal origin) and rarely from metastatic tumors in the skin (such as rhabdomyosarcoma and neuroblastoma).…”

“…The superficial variant may be less aggressive than the more common bony and deep soft tissue counterparts with an apparently favorable outcome [ 3 - 5 ]. This tumor, being seen principally in children, afflicts, occasionally, elderly individuals.…”