AimsThe present study employed a network analysis approach to scrutinize a pig supply chain in a repeated outbreak province for human streptococcosis in Thailand and identified important actors that should be focused on for tailoring appropriate interventions.Methods and ResultsNakhon Sawan province was chosen as the study site as the cases of human streptococcosis have been consecutively reported since 2014, with the number of cases ranging from 21 to 63. A questionnaire survey was used to collect data from actors along the pig supply chain, including pig farms, slaughterhouses, pork sellers, restaurants and customers. A one‐mode‐directed network was then constructed. Degree and betweenness centrality values were measured. We found that the supply chain of pork products comprised 314 nodes and 296 directed ties. A retailer got the highest overall degree, out‐degree and betweenness centrality values at 35, 34, and 65.3, respectively. For in‐degree centrality, the highest was identified in a customer at 9. Interestingly, this customer bought pork products from nine different mobile groceries.ConclusionsBoth public health and veterinary authorities should extend their surveillance activities to cover all actors in the supply chain to strengthen overall disease prevention and control for streptococcosis.