SARS‐CoV‐2 and pediatric solid organ transplantation: Current knowns and unknowns

Abstract

The COVID‐19 pandemic has proven to be a challenge in regard to the clinical presentation, prevention, diagnosis, and management of SARS‐CoV‐2 infection among children who are candidates for and recipients of SOT. By providing scenarios and frequently asked questions encountered in routine clinical practice, this document provides expert opinion and summarizes the available data regarding the prevention, diagnosis, and management of SARS‐CoV‐2 infection among pediatric SOT candidates and recipients and highlights ongoing knowledge gaps requiring further study. Currently available data are still lacking in the pediatric SOT population, but data have emerged in both the adult SOT and general pediatric population regarding the approach to COVID‐19. The document provides expert opinion regarding prevention, diagnosis, and management of SARS‐CoV‐2 infection among pediatric SOT candidates and recipients.

COVID-19 in immunocompromised children and adolescents

“…Data of pediatric patients who underwent solid organ transplantation showed that immunosuppression was not an additional risk factor for severe or complicated COVID-19, showing that most had mild or moderate disease severity like the general population. 42,[48][49][50][51][52]…”