SARS-CoV-2 variants and the global pandemic challenged by vaccine uptake during the emergence of the Delta variant: A national survey seeking vaccine hesitancy causes

Aljamaan, Fadi; Temsah, Mohamad-Hani; Alhasan, Khalid; Alenezi, Shuliweeh; Alhaboob, Ali; Alrabiaah, Abdulkarim; Batais, Mohammed Ali; Alshahrani, Fatimah; Assiri, Rasha; Bafaqih, Hind; Alaraj, Ali; Qadrah, Bedoor Al; Alhaidary, Abdulilah; Saad, Khaled M.; Saddik, Basema; Halwani, Rabih; Rabaan, Ali A.; Alsubaie, Sarah; Barry, Mazin; Al‐Tawfiq, Jaffar A.

doi:10.1016/j.jiph.2022.06.007

Cited by 15 publications

(9 citation statements)

References 67 publications

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“…The reasons for hesitating to and deciding not to get vaccinated uncovered in our study parallel those mentioned in the literature [ 51 , 52 ]. Lack of confidence and knowledge is the main reason for vaccine hesitancy and non-vaccination.…”

Section: Discussionsupporting

confidence: 83%

Talking about the Vaccine after the Pandemic: A Cross-Sectional Study among Youth in Turkey and Ethical Issues

et al. 2023

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Examining the factors that affect the vaccination rate among young people in an ethical frame can support vaccination promotion. Therefore, this study will elaborate, through an ethical lens, on young people’s hesitation about and decisions regarding getting vaccinated. The cross-sectional study was conducted with 2428 people aged 15–30 in Turkey in June 2022. The questionnaire included the following subtitles: psycho-social situation, health services and health policies, COVID-19 vaccine, and predictions about life and health after the pandemic. The average age was 22.9 years. In the study sample, 80% were vaccinated, while 20% were not. Vaccinated participants acted more cautiously to protect their health. Receiving accurate and sufficient information on proposed vaccines affects vaccination status. The primary reason for getting vaccinated was “to protect their health, families, and relatives”, and the primary reason for not getting vaccinated was “not trusting the vaccine content or the country where the vaccine was produced”. Specifically, those vaccinated felt more relaxed physically, psychologically, and socially. In addition, the expectations for the future of those vaccinated were significantly higher. Accurate and adequate information is essential for reducing vaccine hesitancy. In addition, promoting prosocial behaviors in young people and highlighting related values will support vaccination.

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Section: Discussionsupporting

confidence: 83%

Talking about the Vaccine after the Pandemic: A Cross-Sectional Study among Youth in Turkey and Ethical Issues

et al. 2023

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“…For these reasons, efforts should be made to refute any misinformation spread on social media, especially with the emergence of variants. 34 The strength of this study is the fact that it is one of the first studies to examine changes in parents' attitudes towards childhood vaccines during the COVID-19 pandemic and to evaluate parents' attitudes towards childhood vaccines before and after the COVID-19 pandemic. However, it has some limitations.…”

Section: Discussionmentioning

confidence: 99%

“…It is inevitable that this hesitation against COVID‐19 vaccines will be reflected in the behavior of parents towards childhood vaccines. For these reasons, efforts should be made to refute any misinformation spread on social media, especially with the emergence of variants 34 …”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, the emergence of SARSCoV-2 variants such as Delta and Omicron has caused a significant debate on the efficacy of COVID-19 vaccines since 34% of vaccinated people developed COVID-19 disease. 33,34 This ongoing debate contributes to the hesitancy against vaccines for COVID-19 among healthcare professionals as well as the public. In addition, participants who rely on social media platforms are quite hesitant to get vaccinated.…”

Section: Discussionmentioning

confidence: 99%

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Changes in parents' attitudes towards childhood vaccines during COVID‐19 pandemic

Duran

Duran²,

Acunaş³

et al. 2023

Pediatrics International

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Background: Concerns about the safety and adverse reactions of rapidly‐developed vaccines against COVID‐19 contributed to parents' vaccine hesitancy and this situation created an opportunity for anti‐vaccine campaigners. The aim of this study was to examine the changes in parents' attitudes towards childhood vaccines during COVID‐19 pandemic.Methods: In this cross‐sectional study, parents of children who applied to the outpatient clinic of pediatric department of Trakya University Hospital, Edirne, Türkiye, between August 2020 and February 2021 were recruited into two study groups according to COVID‐19 peak time in Türkiye. Group 1 included parents of children who applied after first peak of the COVID‐19 pandemic and Group 2 included parents of children who applied after second peak. The World Health Organization 10‐item Vaccine Hesitancy Scale (WHO‐VHS) was applied to each group.Results: A total of 610 parents agreed to participate in the study. Group 1 and 2 consisted of 160 and 450 parents, respectively. While the number of parents who were hesitant about childhood vaccines was 17 (10.6%) in Group 1, it was 90 (20%) in Group 2. A statistically significant difference was found between the two groups (p = 0.008). The (WHO‐VHS) mean ± SD score was found to be higher in Group 2 (23.7 ± 6.9) than Group 1 (21.3 ± 7.3) (p < 0.001). The WHO‐VHS‐ mean ± SD scores of parents who experienced COVID‐19 infection themselves or their family or acquaintances were significantly lower than those who did not (20.0 ± 6.5 vs. 24.7 ± 6.9) (p < 0.001).Conclusions: The hesitant attitudes towards childhood and COVID‐19 vaccines were low in parents who directly or indirectly experienced COVID‐19 or were worried about the devastating effects of this disease. However, it was shown that as the COVID‐19 pandemic progressed, parents' hesitations towards childhood vaccines increased.

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“…Although most reported cases were self-limited and the benefits of the COVID-19 vaccine in preventing COVID-19 and severe disease outweigh the risks of myocarditis, 5,6,8 the concern about myocarditis as a side effect reduces the willingness of adolescents to be vaccinated. 9,10 Therefore, further investigation into cardiac changes after vaccination is needed to establish public trust in vaccines.…”

Section: Introductionmentioning

confidence: 99%

Echocardiographic function evaluation in adolescents following BNT162b2 Pfizer-BioNTech mRNA vaccination: A preliminary prospective study

Hsu,

Jeng

2023

Journal of the Chinese Medical Association

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Background: Vaccination against coronavirus disease 2019 (COVID-19) is crucial for preventing and minimizing illness. Myocarditis and pericarditis after mRNA COVID-19 vaccination in adolescents and young adult males have been reported. Most of the studies in this area rely on retrospective symptom reporting, especially for adolescents experiencing myocarditis as a potential side effect. However, prospective post-vaccination echocardiographic evaluation is rare. Methods: The study enrolled adolescents aged 12 to 15 years who received the second dose of the BNT162b2 mRNA-Pfizer-BioNTech vaccine (BNT vaccine). Serial echocardiographic examinations were conducted at baseline before vaccination, followed by subsequent assessments on days 2, 7, 14, and 28 to identify any notable differences or abnormal changes in cardiac function. Clinical symptom assessments were also recorded during each follow-up. Results: The study included 25 adolescents, comprising 14 males and 11 females, who completed the four follow-ups. Their mean age was 14 ± 1 years. The average interval between the first and second BNT vaccine doses was 90 ± 7 days. Ejection fraction values were 73.8% ± 5.2% at baseline and 75.7% ± 5.2% at subsequent assessment time points (75.5% ± 4.6%, 75.7% ± 4.5%, 75.79% ± 4.5%, and 77.8% ± 5.9% at day 2, 7, 14, and 28, respectively). The cardiac function remained stable across all time points, with no significant differences observed between male and female participants. Within post-vaccination 48 hours, 18 (72%) of the enrolled adolescents experienced temporary discomfort symptoms, which completely resolved by the final follow-up on the 28th day after vaccination. Conclusion: Although adolescents vaccinated with the second dose of BNT vaccine commonly experienced transient post-vaccination discomfort, the serial echocardiographic examinations did not reveal any significant deterioration of cardiac function within 28 days. Further studies are required to investigate the incidence of SARS-CoV-2 mRNA vaccination-associated myocarditis in adolescents and the related mechanisms.

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SARS-CoV-2 variants and the global pandemic challenged by vaccine uptake during the emergence of the Delta variant: A national survey seeking vaccine hesitancy causes

Cited by 15 publications

References 67 publications

Talking about the Vaccine after the Pandemic: A Cross-Sectional Study among Youth in Turkey and Ethical Issues

Talking about the Vaccine after the Pandemic: A Cross-Sectional Study among Youth in Turkey and Ethical Issues

Changes in parents' attitudes towards childhood vaccines during COVID‐19 pandemic

Echocardiographic function evaluation in adolescents following BNT162b2 Pfizer-BioNTech mRNA vaccination: A preliminary prospective study

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