Over the last two decades, a small group of researchers repeatedly crossed the Greenland interior skiing along a 700-km long route from east to west, acquiring precise GNSS measurements at exactly the same locations. Four such elevation profiles of the ice sheet measured in 2002, 2006, 2010 and 2015 were differenced and used to analyze the surface elevation change. Our goal is to compare such locally measured GNSS data with independent satellite observations. First, we show an agreement in the rate of elevation change between the GNSS data and satellite radar altimetry (ERS, Envisat, CryoSat-2). Both datasets agree well (2002–2015), and both correctly display local features such as an elevation increase in the central part of the ice sheet and a sharp gradual decline in the surface heights above Jakobshavn Glacier. Second, we processed satellite gravimetry data (GRACE) in order for them to be comparable with local GNSS measurements. The agreement is demonstrated by a time series at one of the measurement sites. Finally, we provide our own satellite gravimetry (GRACE, GRACE-FO, Swarm) estimate of the Greenland mass balance: first a mild decrease (2002–2007: −210 ± 29 Gt/yr), then an accelerated mass loss (2007–2012: −335 ± 29 Gt/yr), which was noticeably reduced afterwards (2012–2017: −178 ± 72 Gt/yr), and nowadays it seems to increase again (2018–2019: −278 ± 67 Gt/yr).