Magnetic reconnection is a fundamental process in solar system and astrophysical plasmas, through which stored magnetic energy associated with current sheets is converted into thermal, kinetic and wave energy [1][2][3][4] . Magnetic reconnection is also thought to be a key process involved in shedding internally produced plasma from the giant magnetospheres at Jupiter and Saturn through topological reconfiguration of the magnetic field 5,6 . The region where magnetic fields reconnect is known as the di usion region and in this letter we report on the first encounter of the Cassini spacecraft with a di usion region in Saturn's magnetotail. The data also show evidence of magnetic reconnection over a period of 19 h revealing that reconnection can, in fact, act for prolonged intervals in a rapidly rotating magnetosphere. We show that reconnection can be a significant pathway for internal plasma loss at Saturn 6