Background and objective: Scabies, known as the seven-year itch, is a contagious skin infestation by the mite Sarcoptes scabiei that causes a pruritic skin eruption. Scabies is endemic in most of the communities of the developing world. This study aimed to assess the quality of life of scabies patients, taking into consideration the demographic profile and clinical presentation of patients in Erbil. Methods: In this cross-sectional study, 107 scabies patients attending a private dermatology clinic were recruited. Dermatology Quality of Life Index questionnaire was used for data collection. Results: More than half (51.4%) of the patients were less than 30 years of age, including 58.9% males, 70.1% of them were married, and 67.3% were living in the urban area. More than 84% of the study sample’s quality of life was very large and extremely large affected. The overall mean of the quality of life scores was 14.95±4.5 with no significant association between the overall quality of life scores to disease severity and certain sociodemographic characteristics of the patients. The mean scores of the two domains of embarrassment and shopping were significantly associated with the male gender (P = 0.003 and 0.021, respectively). However, 40.2%, 35.5%, and 29% of the patients reported that the disease affected very much on their shopping, clothing, and working activities, respectively. Conclusion: The disease had caused a significant effect on patients' lives, with no significant association between the severity of the disease and overall quality of life scores. The disease in its mild, moderate, and severe forms adversely affected patient lives. The commonest quality of life scores were those in the range of 11-20. Keywords: Quality of life; Scabies; Erbil; Iraq.