Scalp metastasis from malignant fibrous histiocytoma of bone

Kubo, Toru; Shimose, Shoji; Matsuo, Toshihiro; Arihiro, Koji; Ochi, Mitsuo

doi:10.1016/j.jaad.2008.06.039

Cited by 13 publications

(19 citation statements)

References 21 publications

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“…Women were more represented with the 53.7% (66/123) of cases, compared to the 46.3% (57/123) of men . Median age of AN at onset was 59 (IQR: 47–68).…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the primary site of malignancy, gastrointestinal (GI) tract accounted for 24.4% (30/123), breast for 17.9% (22/123) of cases, kidney for 8.1% (10/123), lung for 7.3% (9/123), thyroid for 7.3% (9/123), uterus for 6.5% (8/123), central nervous system (CNS) for 6.5% (8/123), liver for 3.3% (4/123) and other anatomic areas for 18.7% (23/123) of cases …”

Section: Resultsmentioning

confidence: 99%

“…Concerning histologic subtype of the primary tumour, carcinoma was the most reported with 53.7% (66/123) cases; of these, 38.2% (47/123) were adenocarcinomas, 7.3% (9/123) were squamous cell carcinomas and 0.8% (1/123) was a small cell carcinoma; while, in 7.3% (9/123) of cases, the type of carcinoma was not further specified . Regarding the remaining cases, 3.3% (4/123) primary tumours were leyomyosarcomas, 1.6% (2/123) were meningiomas, 40.7% (50/123) were other tumour subtypes and in one case of breast cancer, the histologic subtype was unknown (Table ) …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Alopecia neoplastica as a sign of visceral malignancies: a systematic review

Paolino

Pampena

Grassi

et al. 2019

Acad Dermatol Venereol

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Alopecia neoplastica (AN) from visceral tumours is a rare form of cutaneous metastasis in which internal malignancies spread to the scalp. The diagnosis of AN may be very challenging, especially when its onset precedes the diagnosis of the primary tumour. We aimed to improve the knowledge on AN, highlighting that in case of scarring localized alopecia, a differential diagnosis with metastasis should always be considered. We performed a systematic review to describe the main demographic and clinical features associated with AN from visceral malignancies; a survival analysis was also performed. In 118 reports, accounting for 123 patients, we found that women were more affected by AN than men (53.7% vs. 46.3%). The most frequent site of the primary tumour was the gastrointestinal tract (24.4%), followed by breast (17.9%), kidney (8.1%), lung (7.3%), thyroid (7.3%), uterus (6.5%), central nervous system (6.5%), liver (3.3%) and other anatomic areas for 18.7% of cases. Furthermore, in more than half of the cases (66.1%), AN lesions were single and were mainly diagnosed after the primary visceral tumour (71.5%). Finally, survival analysis highlighted a lower progression‐free survival in men; while, no significant differences in overall survival were reported among genders. In conclusion, metastatic skin disease should always be taken into consideration when dealing with patients with localized scarring alopecia.

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“…Women were more represented with the 53.7% (66/123) of cases, compared to the 46.3% (57/123) of men . Median age of AN at onset was 59 (IQR: 47–68).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Alopecia neoplastica as a sign of visceral malignancies: a systematic review

Paolino

Pampena

Grassi

et al. 2019

Acad Dermatol Venereol

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“…[ 8 9 ] Surgery in the form of wide excision is the primary modality of management of MFH. [ 3 ] Adjuvant radiotherapy and chemotherapy have been used either alone or in various combinations in an attempt to better the survival outcomes; however, no firm conclusions can be drawn with regards to their effectiveness. [ 4 ] They have been more commonly used in patients with large unresectable tumors and in the setting of metastatic disease.…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] The incidence of malignant neoplasms in the scalp and scalp ranges from 0 to 7.7%, a great majority of them are in fact believed to be metastatic rather than primary neoplasms. [ 2 3 ] Malignant fibrous histiocytoma (MFH) is the most common primary soft tissue sarcoma of late adult life and its occurrence is rare in the pediatric population. We present an unusual case of a primary MFH involving the scalp of a 5-year-old child and discuss its unusual clinical presentation and its management.…”

Section: Introductionmentioning

confidence: 99%

Malignant fibrous histiocytoma of the scalp: A rare differential with a dramatic clinical presentation

Krishnamurthy

2014

J Indian Assoc Pediatr Surg

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Malignant fibrous histiocytoma (MFH) a pleomorphic sarcoma of uncertain origin was first described by O’Brien and Stout in 1964. It is the most common primary soft tissue sarcoma of late adult life; its occurrence is rare in the pediatric population. MFHs are commonly known to arise in the extremities and the trunk although it can occur almost anywhere in the body. MFH of the scalp is extremely rare; moreover, there is paucity of literature with regards to prevalence of scalp and skull neoplasms. We present an unusual case of a primary MFH involving the scalp of a 5-year-old child and discuss its unusual clinical presentation, histology with immunohistochemistry correlation and its management. Reviewing the literature of primary MFH of the scalp, our patient to the best of our knowledge, is probably the youngest case reported so far.

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