“…Out of the 24 studies included, eight were from India, 16 , 17 , 21 , 22 , 23 , 24 , 25 , 26 two from Iran, 12 , 27 two from Brazil, 28 , 29 two from Thailand, 30 , 31 one study each from Egypt, 13 Saudi Arabia, 32 Lebanon, 33 Turkey, 14 Austria, 15 China, 34 United Arab Emirates, 35 Germany, 36 and Bulgaria. 37 All the studies were conducted in-vitro with a sample size ranging from 10 to 26. The included teeth had a straight canal in 11 studies, 12 , 16 , 17 , 21 , 24 , 25 , 30 , 32 , 36 , 37 , 38 oval in one study 14 and round in two studies.…”