Scar Assessment: Current Problems and Future Solutions

Ps, Powers; Sarkar, Sudeep; Db, Goldgof; Cw, Cruse; Lv, Tsap

doi:10.1097/00004630-199901001-00011

Cited by 99 publications

(49 citation statements)

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“…Wounds with prolonged healing can be considered most risky for impairment of such process and undue scar formation. Although evaluation of scar development seems necessary, this is still a neglected area, and yet there is no agreement on the best method for scar assessment (Powers et al, 1999). In the current study, visual inspection of scars was performed till 14 days post wounding as a simple method for monitoring of the presence or absence of scars.…”

Section: Scar Monitoringmentioning

confidence: 99%

Novel curcumin-loaded gel-core hyaluosomes with promising burn-wound healing potential: Development, in-vitro appraisal and in-vivo studies

El-Refaie

Elnaggar

El-Massik

et al. 2015

International Journal of Pharmaceutics

120

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Section: Scar Monitoringmentioning

confidence: 99%

Novel curcumin-loaded gel-core hyaluosomes with promising burn-wound healing potential: Development, in-vitro appraisal and in-vivo studies

El-Refaie

Elnaggar

El-Massik

et al. 2015

International Journal of Pharmaceutics

120

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“…Such measurements, however, are restricted to the skin's surface and depend heavily on the experience of medical professionals, wound condition and treatment history (8). Attempts have been made to quantify such measurements, such as with the use of the Vancouver scar scale and the Manchester scar proforma, but these too suffer from significant subjective drawbacks (9,10). Currently, biopsies provide the best objective assessment of wound recovery, but this technique causes further tissue destruction and increases the risk of infection (11).…”

Section: Introductionmentioning

confidence: 99%

Optical coherence tomography angiography monitors human cutaneous wound healing over time

Deegan¹,

Men²,

Li³

et al. 2018

Quant. Imaging Med. Surg.

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Background: In vivo imaging of the complex cascade of events known to be pivotal elements in the healing of cutaneous wounds is a difficult but essential task. Current techniques are highly invasive, or lack the level of vascular and structural detail required for accurate evaluation, monitoring and treatment. We aimed to use an advanced optical coherence tomography (OCT)-based angiography (OCTA) technique for the noninvasive, high resolution imaging of cutaneous wound healing.Methods: We used a clinical prototype OCTA to image, identify and track key vascular and structural adaptations known to occur throughout the healing process. Specific vascular parameters, such as diameter and density, were measured to aid our interpretations under a spatiotemporal framework.Results: We identified multiple distinct, yet overlapping stages, hemostasis, inflammation, proliferation, and remodeling, and demonstrated the detailed vascularization and anatomical attributes underlying the multifactorial processes of dermatologic wound healing.Conclusions: OCTA provides an opportunity to both qualitatively and quantitatively assess the vascular response to acute cutaneous damage and in the future, may help to ascertain wound severity and possible healing outcomes; thus, enabling more effective treatment options.

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“…Although scar assessment seems essential, this is still a neglected area, and there is still no consensus on the ideal method of scar evaluation, in spite of the many scales and tools that have been developed during the last decades [34]. Adequate assessment of scars is, however, important in the clinical evaluation and follow-up, but it is also essential to compare different wound or scar treatment modalities [35][36][37][38][39][40][41]. Moreover, for medico-legal reasons, an objective scar evaluation can be required, e.g., for reimbursement of treatment and proof of disability.…”

Section: Introductionmentioning

confidence: 99%

“…), but also by using technically advanced and objective devices (scar tools) analyzing one or more variables in a more reproducible way (spectrometry, ultrasound etc.) [36,39,40,[42][43][44][45][46][47][48][49][50]. The objective of this study was to provide an analysis and critical overview as to which scar scales have been developed to assess the physical aspect of burn scars, and what their role is in burn assessment.…”

Section: Introductionmentioning

confidence: 99%