“…While scatter suppression approaches try to reduce the amount of scattered X-rays reaching the detector using anti-scatter grids or collimators B Joscha Maier joscha.maier@dkfz.de 1 German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany [26], scatter estimation approaches aim at deriving an estimate of the scatter distribution that is used to correct the acquired projection data [27]. Thereby, the scatter estimate can either be derived using dedicated hardware such as beam blockers or primary modulation grids [3,7,8,20,24,28,38,39] or using software-based approaches that rely on physical or empirical models to predict X-ray scattering [1,2,11,17,18,21,22,30,[32][33][34]36,37]. Among these methods the gold standard is to use a Monte Carlo (MC) photon transport code [27].…”