Schätzung der Zahl der HIV-Neuinfektionen und der Gesamtzahl von Menschen mit HIV in Deutschland

Heiden, Matthias an der; Marcus, Ulrich; Kollan, Christian; Schmidt, Daniel; Voss, Lieselotte; Gunsenheimer‐Bartmeyer, Barbara; Bremer, Viviane

doi:10.17886/epibull-2018-056.2

Cited by 2 publications

(1 citation statement)

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“…As a consequence of regional variability in epidemiology, absolute numbers of patients treated for AIDS-related complications differ between high-incidence countries, such as South Africa, and low-incidence countries, such as Germany [ 14 ]. Nevertheless, ICU staff worldwide is thought to face similar challenges in treatment of this vulnerable predefined population.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors in HIV-1 Positive Patients on the Intensive Care Unit: A Single Center Experience from a Tertiary Care Hospital

Schulze

Möhr

Sackarnd

et al. 2023

Viruses

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HIV-positive patients with acquired immunodeficiency syndrome (AIDS) often require treatment on intensive care units (ICUs). We aimed to present data from a German, low-incidence region cohort, and subsequently evaluate factors measured during the first 24 h of ICU stay to predict short- and long-term survival, and compare with data from high-incidence regions. We documented 62 patient courses between 2009 and 2019, treated on a non-operative ICU of a tertiary care hospital, mostly due to respiratory deterioration and co-infections. Of these, 54 patients required ventilatory support within the first 24 h with either nasal cannula/mask (n = 12), non-invasive ventilation (n = 16), or invasive ventilation (n = 26). Overall survival at day 30 was 77.4%. While ventilatory parameters (all p < 0.05), pH level (c/o 7.31, p = 0.001), and platelet count (c/o 164,000/µL, p = 0.002) were significant univariate predictors of 30-day and 60-day survival, different ICU scoring systems, such as SOFA score, APACHE II, and SAPS 2 predicted overall survival (all p < 0.001). Next to the presence or history of solid neoplasia (p = 0.026), platelet count (HR 6.7 for <164,000/µL, p = 0.020) and pH level (HR 5.8 for <7.31, p = 0.009) remained independently associated with 30-day and 60-day survival in multivariable Cox regression. However, ventilation parameters did not predict survival multivariably.

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Section: Introductionmentioning

confidence: 99%

Risk Factors in HIV-1 Positive Patients on the Intensive Care Unit: A Single Center Experience from a Tertiary Care Hospital

Schulze

Möhr

Sackarnd

et al. 2023

Viruses

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Diagnostik und Therapie bei HIV-Infektion – was muss der Hausarzt wissen?

Ankert¹,

Rößler²,

Flössner³

et al. 2019

Dtsch med Wochenschr

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According to the Robert Koch Institute, the estimated HIV prevalence in Germany is 86 100. On-third of the affected persons is over 50 years old. Overall, the prognosis of patients with HIV infection depends crucially on the time of diagnosis. The unfounded stigmatization of affected patients stands in the way of today's treatment options as it did 30 years ago. Every practice of primary care must also take into consideration the medical care of HIV-infected people. The purpose of this article is to make the general practitioner aware of this topic and to prepare for the necessary procedure in everyday practice in this rare but not unlikely situation.

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Schätzung der Zahl der HIV-Neuinfektionen und der Gesamtzahl von Menschen mit HIV in Deutschland

Cited by 2 publications

References 0 publications

Risk Factors in HIV-1 Positive Patients on the Intensive Care Unit: A Single Center Experience from a Tertiary Care Hospital

Risk Factors in HIV-1 Positive Patients on the Intensive Care Unit: A Single Center Experience from a Tertiary Care Hospital

Diagnostik und Therapie bei HIV-Infektion – was muss der Hausarzt wissen?

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