Schema and Motor-Memory Consolidation

King, Bradley R.; Dolfen, Nina; Gann, Mareike A.; Renard, Zenzi; Swinnen, Stephan P.; Albouy, Geneviève

doi:10.1177/0956797619847164

Cited by 20 publications

(34 citation statements)

References 38 publications

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“…An explicit bimanual version of the serial reaction time task (SRTT; ( Nissen and Bullemer, 1987 )) previously used in our group ( King et al, 2019 ) that was coded and implemented with the Psychophysics Toolbox in Matlab ( Brainard, 1997 ) was used in this study. Participants were lying in the scanner with a specialized MR-compatible keyboard placed on their lap.…”

Section: Methodsmentioning

confidence: 99%

Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation

et al. 2021

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While it is widely accepted that motor sequence learning (MSL) is supported by a prefrontal-mediated interaction between hippocampal and striatal networks, it remains unknown whether the functional responses of these networks can be modulated in humans with targeted experimental interventions. The present proof-of-concept study employed a multimodal neuroimaging approach, including functional magnetic resonance (MR) imaging and MR spectroscopy, to investigate whether individually-tailored theta-burst stimulation of the dorsolateral prefrontal cortex can modulate responses in the hippocampus and the basal ganglia during motor learning. Our results indicate that while stimulation did not modulate motor performance nor task-related brain activity, it influenced connectivity patterns within hippocampo-frontal and striatal networks. Stimulation also altered the relationship between the levels of gamma-aminobutyric acid (GABA) in the stimulated prefrontal cortex and learning-related changes in both activity and connectivity in fronto-striato-hippocampal networks. This study provides the first experimental evidence, to the best of our knowledge, that brain stimulation can alter motor learning-related functional responses in the striatum and hippocampus.

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Section: Methodsmentioning

confidence: 99%

Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation

et al. 2021

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“…In addition to the repeated reactivation-induced strengthening and stabilization of the newly acquired memory trace at the local synaptic level, there is accumulating evidence supporting the existence of a gradual reorganization of temporary formed representations over distributed and long-lasting brain networks (e.g. [73,74]; see also [9,16], for reviews). In accordance with this systems level concept, work from our laboratory looking at procedural memory consolidation has revealed that motor memory traces are not only strengthened during sleep, but undergo qualitative representational changes (e.g.…”

Section: Neural Substrates Associated With Spindlerelated Memory Consolidationmentioning

confidence: 99%

A sleep spindle framework for motor memory consolidation

Boutin

Doyon

2020

Phil. Trans. R. Soc. B

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Sleep spindle activity has repeatedly been found to contribute to brain plasticity and consolidation of both declarative and procedural memories. Here we propose a framework for motor memory consolidation that outlines the essential contribution of the hierarchical and multi-scale periodicity of spindle activity, as well as of the synchronization and interaction of brain oscillations during this sleep-dependent process. We posit that the clustering of sleep spindles in ‘trains', together with the temporally organized alternation between spindles and associated refractory periods, is critical for efficient reprocessing and consolidation of motor memories. We further argue that the long-term retention of procedural memories relies on the synchronized (functional connectivity) local reprocessing of new information across segregated, but inter-connected brain regions that are involved in the initial learning process. Finally, we propose that oscillatory synchrony in the spindle frequency band may reflect the cross-structural reactivation, reorganization and consolidation of motor, and potentially declarative, memory traces within broader subcortical–cortical networks during sleep. This article is part of the Theo Murphy meeting issue ‘Memory reactivation: replaying events past, present and future'.

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“…Sleep, and specific plasticity-related sleep features such as spindles and slow waves that are present in non-rapid-eye-movement (NREM) sleep, are thought to support declarative schema formation and subsequent integration of novel information [ 1,[11][12][13][14][15][16][17] although see 18 ]. While our previous results hinted that sleep may be crucial for the integration of novel motor information into a previously-acquired schema 7 , the design employed could not differentiate the specific effects of sleep from the influence of time.…”

Section: Introductionmentioning

confidence: 70%

Sleep does not influence schema-facilitated motor memory consolidation

Reverberi

Dolfen

Roy

et al. 2022

Preprint

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Study ObjectivesNovel information is rapidly learned when it is compatible with previous knowledge. This “schema” effect, initially described for declarative memories, was recently extended to the motor memory domain. Importantly, this beneficial effect was only observed 24 hours – but not immediately – following motor schema acquisition. Given the established role of sleep in memory consolidation, we hypothesized that sleep following the initial learning of a schema is necessary for the subsequent rapid integration of novel motor information.MethodsTwo experiments were conducted to investigate the effect of diurnal and nocturnal sleep on schema-mediated motor sequence memory consolidation. In Experiment 1, participants first learned an 8-element motor sequence through repeated practice (Session 1). They were then afforded a 90-minute nap opportunity (N=25) or remained awake (N=25) before learning a second motor sequence (Session 2) which was highly compatible with that learned prior to the sleep/wake interval. Experiment 2 was similar; however, Sessions 1 and 2 were separated by a 12-hour interval that included nocturnal sleep (N=28) or only wakefulness (N=29).ResultsFor both experiments, we found no group differences in motor sequence performance (reaction time and accuracy) following the sleep/wake interval. Furthermore, in Experiment 1, we found no correlation between sleep features (non-REM sleep duration, spindle and slow wave activity) and post-sleep behavioral performance.ConclusionsThe results of this research suggest that integration of novel motor information into a cognitive-motor schema does not specifically benefit from post-learning sleep.

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Schema and Motor-Memory Consolidation

Cited by 20 publications

References 38 publications

Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation

Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation

A sleep spindle framework for motor memory consolidation

Sleep does not influence schema-facilitated motor memory consolidation

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