Schistosoma mansoni: Cytotoxicity of hemocytes from susceptible snail hosts for sporocysts in plasma from resistant Biomphalaria glabrata

Bayne, Christopher J.; Buckley, Patricia M.; DeWan, Peggy C.

doi:10.1016/0014-4894(80)90043-0

Cited by 113 publications

(37 citation statements)

References 21 publications

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“…Such defense mechanisms by the parasite appear to be essential for survival during the first few days of parasitic life. On the other hand, the defense mechanisms of the parasite may not be functional in resistant snails as evidenced by several in vitro studies (9)(10)(11) (1 hr). Practically all epidermal plates are detached at this stage and the organism is devoid of protective surface covering except for the epidermal ridges.…”

mentioning

confidence: 99%

Review: SCHISTOSOMA MANSONI: THE ULTRASTRUCTURE OF LARVAL MORPHOGENESIS IN BIOMPHALARIA GLABRATA AND OF ASSOCIATED HOST-PARASITE INTERACTIONS

Sc¹

1996

JJMSB

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mentioning

confidence: 99%

Review: SCHISTOSOMA MANSONI: THE ULTRASTRUCTURE OF LARVAL MORPHOGENESIS IN BIOMPHALARIA GLABRATA AND OF ASSOCIATED HOST-PARASITE INTERACTIONS

Sc¹

1996

JJMSB

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“…bacteria ; their cytoskeletal mobility and the adaptations of their plasma membranes encapsulate foreign 15 organisms , and these cells also cooperate with several humoral defense factors. There have been many studies that have attempted to elucidate the complex parasite/host 16,17,18,19 interaction in this model .…”

Section: Resultsmentioning

confidence: 99%

Hemocyte production in Biomphalaria glabrata snails after exposure to different Schistosoma mansoni infection protocols

Santos¹,

Santos²,

Rodrigues³

2011

Rev Pan-Amaz Saude

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The objective of this work was to determine the profile of the cellular defense system during mansonic infection. Specifically, this study assessed the number of hemocytes that were produced and released into the hemolymph in response to the parasitic infection. The quantification of the Biomphalaria glabrata hemocytes was performed on groups of snails at 1, 5, 10, 15, 20 and 30 days post-infection that had been individually infected with 5, 10, 15 or 30 Schistosoma mansoni miracidia. The results revealed that B. glabrata possesses a cellular defense mechanism that is characterized by the release of hemocytes into the hemolymph. The maximum peak of cellular production occurred 24 hours after infection, and there was a significant reduction in the hemocyte concentration over the following 10 days. However, at 15 days post-infection, there was a second increase in the cellular hemocyte production, although this was not as strong as the primary peak. At 30 days post-infection, there was another moderate rise in the cellular hemocyte production. Based on this cellular response profile, the defense system of the snail appears to be effective immediately following infection, but the response does not ensure the destruction of all parasites during the course of the infection.

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“…São numerosas as pesquisas que demonstram a presença de mecanismos imunológicos do molusco, agindo contra as larvas de S. mansoni (Michelson 9 , 1964; Lie e col. 8 , 1980; Bayne e col. 4 . Sabe-se que a larva do S. mansoni, no molusco, pode escapar a esta ação de caráter imunológico por estar envolta com material do pró-prio molusco, não sendo assim reconhecida pelos amebócitos como corpo estranho.…”

Section: Resultsunclassified

Viabilidade de miracídios de Schistosoma mansoni, obtidos de fezes e de granulomas hepáticos de camundongos experimentalmente infectados com a linhagem BH

et al. 1988

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RESUMO: Estudou-se comparativamente a viabilidade, em moluscos hospedeiros, de miracídios de Schistosoma mansoni de duas origens: de ovos eliminados com as fezes e de granulomas hepáticos. Procurou-se saber se havia efeito da origem sobre o número total de cercárias obtidas e sobre o período de eliminação de cercárias. Foram também verificados o período pré-patente da infecção dos moluscos, a sobrevivência do caramujo após a infecção e o sexo das cercárias eliminadas. Concluiu-se que: a) o período pré-patente foi maior nos moluscos infectados por miracídios provenientes de granulomas hepáticos; b) a sobrevivência dos moluscos após a infecção foi maior naqueles infectados por miracídios provenientes de granulomas hepáticos; c) o número de cercadas eliminadas por molusco infectado com miracídios provenientes de granulomas hepáticos foi três vezes maior que o número de cercárias eliminadas por moluscos infectados com miracídios provenientes de ovos eliminados com as fezes.

show abstract

Schistosoma mansoni: Cytotoxicity of hemocytes from susceptible snail hosts for sporocysts in plasma from resistant Biomphalaria glabrata

Cited by 113 publications

References 21 publications

Review: SCHISTOSOMA MANSONI: THE ULTRASTRUCTURE OF LARVAL MORPHOGENESIS IN BIOMPHALARIA GLABRATA AND OF ASSOCIATED HOST-PARASITE INTERACTIONS

Review: SCHISTOSOMA MANSONI: THE ULTRASTRUCTURE OF LARVAL MORPHOGENESIS IN BIOMPHALARIA GLABRATA AND OF ASSOCIATED HOST-PARASITE INTERACTIONS

Hemocyte production in Biomphalaria glabrata snails after exposure to different Schistosoma mansoni infection protocols

Viabilidade de miracídios de Schistosoma mansoni, obtidos de fezes e de granulomas hepáticos de camundongos experimentalmente infectados com a linhagem BH

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