Schneiderian first‐rank symptoms associated with fluvoxamine treatment: a case report

Abstract

This communication describes a patient who developed Schneiderian first-rank symptoms in the course of treatment with fluvoxamine. The patient, a 28-year-old man suffering from panic disorder, developed several first-rank symptoms during fluvoxamine administration. These symptoms abated 1 week after fluvoxamine treatment was discontinued and haloperidol was started. Although haloperidol was discontinued, no further hallucinations or delusions occurred. This finding suggests that fluvoxamine can precipitate Schneiderian first-rank symptoms in some susceptible patients.

Visual Hallucinations During Duloxetine Treatment in a Patient With Major Depressive Disorder

“…In cases of clinical and excessive dosage, many previous reports have demonstrated that selective serotonin reuptake inhibitors (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline) can cause hallucinations and other psychiatric symptoms. [12][13][14][15][16][17][18][19][20][21] Some previous reports have demonstrated that selective serotonin reuptake inhibitors can lead to these symptoms by causing a pharmacological increase in the dopaminergic neurotransmission that occurs through direct dopamine reuptake blocking or stimulation of the postsynaptic 5-HT 2 and 5-HT 3 receptors. 21,22 This serotonergic neurotransmission function may induce hallucinations.…”

A case of serial nightmares and oneiroid state under paroxetine for senile depression

“…Although it is unclear whether paroxetine tends to induce nightmares, any drugs associated with norepinephrine, serotonin, or dopamin can induce nightmares 3 . Indeed, there are a number of reports suggesting the hallucinogenic potential of SSRIs 4–20 . A number of patients who have taken SSRIs combined with other neuroactive drugs or have had organic brain dysfunction have presented with hallucinations 4,5,7–10,15–19 .…”